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Sweetener Additives

21 FDA-listed sweetener substances — safety ratings, regulatory status, adverse event data.

Showing 121 of 21 sweetener additives

Caution3 events

Acesulfame Potassium

Sweetener

Acesulfame potassium (acesulfame K) is a synthetic non-nutritive sweetener approximately 200 times sweeter than sugar. It is widely used in beverages, baked goods, and other food products to provide sweetness without calories.

CAS 55589-62-3View
Safe

Advantame

Sweetener

Advantame is a non-nutritive sweetener derived from aspartame that provides sweetness without calories. It is approximately 20,000 times sweeter than sucrose and is used in various food and beverage products as a sugar substitute.

CAS 714229-20-6View
Avoid

Calcium Cyclamate

Sweetener

Calcium cyclamate is a synthetic non-nutritive sweetener approximately 30-40 times sweeter than sucrose. It was widely used in beverages and processed foods but has been prohibited in many countries, including the United States, due to regulatory decisions based on animal study findings.

CAS 5897-16-5View
Avoid

Cyclamate

Sweetener

Cyclamate is a synthetic non-nutritive sweetener approximately 30-40 times sweeter than sucrose. It was widely used in foods and beverages but has been prohibited in many countries due to regulatory concerns, despite limited evidence of direct human toxicity.

CAS 977016-96-8View
Avoid

Dulcin

Sweetener

Dulcin is a synthetic non-nutritive sweetener that was used in food products during the early-to-mid 20th century. It has been prohibited in most countries, including the United States, due to safety concerns identified in animal studies.

CAS 150-69-6View
Safe5 events

High Fructose Corn Syrup

Sweetener

High Fructose Corn Syrup (HFCS) is a sweetener derived from corn starch through enzymatic processing, containing approximately 55% fructose and 42% glucose. It is widely used in beverages, baked goods, and processed foods as a cost-effective alternative to sucrose.

CAS 977042-84-4View
Safe

Lactose, Hydrolyzed

Sweetener

Hydrolyzed lactose is a nutritive sweetener created by breaking down lactose (milk sugar) into its simpler components, glucose and galactose. It is used in food products as a sweetening agent and is recognized as safe by the FDA.

CAS 977126-93-4View
Avoid

Magnesium Cyclamate

Sweetener

Magnesium cyclamate is a non-nutritive artificial sweetener derived from cyclamic acid. It was used as a sugar substitute in food and beverages but has been prohibited in many countries due to regulatory decisions, despite limited evidence of direct harm in humans.

CAS 7757-85-9View
Safe

Maltose

Sweetener

Maltose is a naturally occurring disaccharide sugar composed of two glucose units, commonly used as a nutritive sweetener in food and beverage products. It provides sweetness and texture benefits while delivering approximately 4 calories per gram, similar to other sugars.

CAS 69-79-4View
Safe

Molasses (saccharum Officinarum L.)

Sweetener

Molasses is a thick, dark byproduct of sugar refining derived from sugarcane (Saccharum officinarum L.). It functions as a nutritive sweetener in foods and beverages, providing sweetness along with minor amounts of minerals and compounds naturally present in sugar cane.

CAS 977001-99-2View
Avoid

P-4000

Sweetener

P-4000 is a non-nutritive synthetic sweetener that was developed as a sugar substitute for food and beverage applications. It has not been approved by the FDA and remains prohibited from use in food products in the United States.

CAS 553-79-7View
Avoid

Potassium Cyclamate

Sweetener

Potassium cyclamate is a synthetic non-nutritive sweetener that was used as a sugar substitute in food and beverages. It has been prohibited in the United States since 1969 due to safety concerns identified in animal studies, though regulatory status varies internationally.

CAS 7758-04-5View
Caution

Saccharin

Sweetener

Saccharin is a synthetic non-nutritive sweetener approximately 300-400 times sweeter than sucrose. It has been used in food and beverages since the early 1900s to provide sweetness without calories and is approved for use by the FDA and regulatory agencies worldwide.

CAS 81-07-2View
Caution

Saccharin, Ammonium Salt

Sweetener

Saccharin, ammonium salt (CAS 6381-61-9) is a non-nutritive synthetic sweetener approximately 300-400 times sweeter than sucrose. It is used in food and beverage products as a sugar substitute to provide sweetness without calories.

CAS 6381-61-9View
Caution

Saccharin, Calcium Salt

Sweetener

Calcium saccharin is the calcium salt form of saccharin, a synthetic non-nutritive sweetener that provides sweetness without calories. It is used in beverages, food products, and tabletop sweeteners to reduce sugar content while maintaining sweet taste.

CAS 6381-91-5View
Avoid

Sodium Cyclamate

Sweetener

Sodium cyclamate is a synthetic non-nutritive sweetener that was used as a sugar substitute in food and beverages. It has been prohibited in the United States since 1969 due to regulatory concerns, though it remains approved in some other countries.

CAS 139-05-9View
Caution

Sucralose

Sweetener

Sucralose is a non-nutritive artificial sweetener approximately 600 times sweeter than sugar. It is widely used in beverages, baked goods, and other food products as a sugar substitute to reduce caloric content.

CAS 56038-13-2View
Safe

Sucrose

Sweetener

Sucrose is a naturally occurring disaccharide sugar composed of glucose and fructose, commonly known as table sugar. It is widely used as a nutritive sweetener in beverages, baked goods, confections, and numerous processed foods to provide sweetness and functional properties like texture and preservation.

CAS 57-50-1View
Caution

Talc

Sweetener

Talc (CAS 14807-96-6) is a naturally occurring mineral silicate used in food manufacturing as a formulation aid, processing aid, and anti-caking agent. While not FDA GRAS-approved, it has been used historically in food applications and serves functions related to texture and surface treatment in various food products.

CAS 14807-96-6View
Safe

Tapioca Starch

Sweetener

Tapioca starch is a carbohydrate extracted from cassava root that functions as both a nutritive sweetener and thickening agent in food products. It is commonly used to improve texture, consistency, and mouthfeel in processed foods while providing calories and carbohydrates.

CAS 977002-81-5View
Safe

Xylitol

Sweetener

Xylitol is a naturally occurring sugar alcohol derived from plant materials like birch wood and corn cobs. It functions as a nutritive sweetener and humectant in food products, providing sweetness comparable to sugar while containing fewer calories and having a lower glycemic impact.

CAS 87-99-0View