Our Verdict: RATING UNKNOWN

Phenylethyl Mercaptan

CAS4410-99-5

Insufficient data to assign a rating

We do not have enough regulatory data to assign a safety rating to this additive at this time.

Adverse Events

0

FDA CFSAN

FDA Recalls

0

OpenFDA

United States

Approved

FDA

European Union

Not_evaluated

EFSA

Phenylethyl Mercaptan — food additive

Phenylethyl mercaptan (CAS 4410-99-5) is an organic sulfur compound used as a flavoring agent in food products. It contributes savory, meaty, and sulfurous aromatic notes to processed foods and beverages.

US Status

Approved

FDA

EU Status

Not_evaluated

EFSA

Adverse Events

0

FDA CFSAN

FDA Recalls

0

OpenFDA

Global Regulatory Status

United States
ApprovedFDA
European Union
Not EvaluatedEFSA
United Kingdom
Not EvaluatedUK FSA
Canada
Not EvaluatedHealth Canada
Australia
Not EvaluatedFSANZ
Japan
Not EvaluatedMHLW
South Korea
Not EvaluatedMFDS
Brazil
Not EvaluatedANVISA
China
Not EvaluatedNHC / GB 2760
India
Not EvaluatedFSSAI
Country data is sourced from official regulatory databases and enriched via AI analysis. Always verify with the relevant national authority before making dietary decisions.

What is Phenylethyl Mercaptan?

Phenylethyl mercaptan is an organosulfur compound with the chemical formula C8H10S. It belongs to the class of molecules known as mercaptans or thiols, characterized by the presence of a sulfhydryl (-SH) functional group. This volatile compound occurs naturally in some foods and is synthetically produced for use as a flavoring agent in the food industry.

Common Uses

Phenylethyl mercaptan is used primarily as a flavoring agent in processed foods and beverages where savory, meaty, or roasted notes are desired. Its applications typically include:

- Meat flavoring systems and meat analogs

- Savory snack seasonings

- Processed meat products

- Broth and gravy formulations

- Ready-to-eat meal components

The compound is valued in the flavor industry for its ability to impart umami and cooked meat characteristics at very low concentrations, where it functions as a flavoring adjuvant that enhances overall sensory profiles.

Safety Assessment

Phenylethyl mercaptan has not been designated as Generally Recognized as Safe (GRAS) by the FDA, meaning it does not have official GRAS status for food use in the United States. However, the compound has no recorded adverse events in the FDA database and no product recalls associated with it.

The safety profile is characterized by limited but available toxicological data. Like other mercaptan compounds used in flavoring, phenylethyl mercaptan is used at extremely low concentrations—typically in the parts per million (ppm) range or lower—which substantially reduces potential exposure risks. The volatile nature of the compound means it may be partially lost during food processing, further reducing actual dietary intake.

Organoleptic thresholds (the minimum concentration at which a substance can be detected by human senses) for mercaptans are generally very low, allowing effective flavoring at minimal use levels. This principle of "use as low as possible" is standard practice in the flavor industry and supports safe application.

Regulatory Status

In the United States, phenylethyl mercaptan does not have GRAS affirmation, which restricts its legal use in conventional food products. However, it may be permitted in certain applications or under specific regulatory pathways depending on the product category and intended use.

Regulatory approaches to flavoring agents vary internationally. The European Union maintains detailed specifications for flavoring compounds through the Flavoring Regulation (EC) 1334/2008, though phenylethyl mercaptan's status within these frameworks may be limited or regional.

Manufacturers wishing to use this compound in food products must comply with applicable regulations in their target markets. In the United States, petitions for GRAS affirmation can be submitted to the FDA if adequate safety data exists.

Key Studies

Scientific literature on phenylethyl mercaptan is limited compared to more widely used flavoring agents. Available research focuses primarily on:

- Sensory properties and flavor applications

- Analytical methods for detection and quantification in food matrices

- Comparative flavor threshold studies among mercaptan compounds

- General toxicological profiles of organosulfur flavoring compounds

Most toxicological data derives from studies on structurally related mercaptan compounds and general sulfur-containing flavor molecules. The lack of specific adverse event reports and recalls suggests acceptable safety margins at intended use levels, though comprehensive chronic toxicity studies specific to this compound may be limited in the public domain.

Research indicates that mercaptan compounds are metabolized relatively rapidly in the body, with sulfur-containing metabolites excreted through normal elimination pathways. The extremely low use concentrations in food applications mean systemic exposure levels remain minimal.

Frequently Asked Questions

What is Phenylethyl Mercaptan?

Phenylethyl mercaptan (CAS 4410-99-5) is an organic sulfur compound used as a flavoring agent in food products. It contributes savory, meaty, and sulfurous aromatic notes to processed foods and beverages.

Is Phenylethyl Mercaptan safe?

Phenylethyl Mercaptan is currently rated "unknown" based on FDA and EFSA data. It is approved in the US and not_evaluated in the EU. There are 0 FDA adverse event reports associated with this additive.

Is Phenylethyl Mercaptan banned in any country?

Phenylethyl Mercaptan is approved in the United States and not_evaluated in the European Union. Review the regulatory status cards above for the most current information.

Data Sources

Data is sourced exclusively from official government databases and updated periodically. This page does not constitute medical advice. Consult a healthcare professional for dietary guidance.