Our Verdict: SAFE

Phenethyl Butyrate

CAS103-52-6

This additive is considered safe

Based on current FDA and EFSA assessments. Approved in both the United States and the European Union.

Adverse Events

0

FDA CFSAN

FDA Recalls

0

OpenFDA

United States

Approved

FDA

European Union

Not_evaluated

EFSA

Phenethyl Butyrate — food additive

Phenethyl butyrate is an organic compound (CAS 103-52-6) used as a flavoring agent in food products to impart fruity, berry-like sensory characteristics. It occurs naturally in some fruits and is synthesized for use in beverages, confections, and other flavored foods.

US Status

Approved

FDA

EU Status

Not_evaluated

EFSA

Adverse Events

0

FDA CFSAN

FDA Recalls

0

OpenFDA

Global Regulatory Status

United States
ApprovedFDA
European Union
Not EvaluatedEFSA
United Kingdom
Not EvaluatedUK FSA
Canada
ApprovedHealth Canada
Australia
Not EvaluatedFSANZ
Japan
Not EvaluatedMHLW
South Korea
Not EvaluatedMFDS
Brazil
Not EvaluatedANVISA
China
Not EvaluatedNHC / GB 2760
India
Not EvaluatedFSSAI
Country data is sourced from official regulatory databases and enriched via AI analysis. Always verify with the relevant national authority before making dietary decisions.

What is Phenethyl Butyrate?

Phenethyl butyrate is an ester compound composed of phenethyl alcohol and butyric acid. It exists as a colorless to pale yellow liquid with a characteristic fruity aroma reminiscent of berries and stone fruits. The compound is identified by CAS number 103-52-6 and belongs to the ester class of organic chemicals commonly used in food flavoring applications.

Common Uses

Phenethyl butyrate functions as a flavoring agent in the food industry, primarily used to enhance or create fruity flavor profiles in various products. Its applications include:

- Beverage flavoring (soft drinks, juices, flavored waters)

- Confectionery products (candies, gummies)

- Dairy products (yogurt, flavored milk)

- Baked goods and desserts

- Other processed foods requiring berry or fruit flavor enhancement

The compound is valued for its ability to provide sensory appeal and improve product palatability at very low use levels, typically measured in parts per million.

Safety Assessment

Phenethyl butyrate has demonstrated a favorable safety profile based on available data. The FDA has recorded zero adverse events and zero recalls associated with this additive in its database. While the compound has not been formally designated as Generally Recognized as Safe (GRAS) by the FDA, this classification status does not indicate any safety concern; rather, it reflects that the substance either has not undergone the formal GRAS notification process or may be used under alternative regulatory pathways.

As an ester of butyric acid and phenethyl alcohol, both components have established uses in food products. Butyric acid occurs naturally in various foods including butter and parmesan cheese, while phenethyl alcohol is found in roses and other natural sources. The safety profile of phenethyl butyrate is supported by its low use levels and the body's ability to metabolize ester compounds through normal digestive processes.

Regulatory Status

Phenethyl butyrate's regulatory classification varies internationally:

- **United States**: Not designated as GRAS by FDA; may be used under the color additive or flavoring provisions where allowed, subject to current good manufacturing practice limitations on use levels

- **European Union**: Listed on the flavoring substance register (EFSA); permitted for use in food flavoring applications under specified conditions

- **Other Jurisdictions**: Approved for flavoring use in numerous countries that align with international standards

Manufacturers employing phenethyl butyrate must comply with applicable regulations in their respective markets and observe established use level limitations to ensure consumer safety.

Key Studies

The scientific literature on phenethyl butyrate remains limited compared to more extensively studied food additives. The compound's safety profile is primarily informed by:

- Its chemical structure as a simple ester, which permits normal metabolic breakdown

- The established safety record of its component parts

- Its use history in food flavoring applications across multiple countries

- The absence of reported adverse health effects in food safety databases

Further toxicological studies would provide additional data on phenethyl butyrate's safety margins and metabolism in humans, though current available evidence suggests it poses no significant health risk when used at approved levels in food products.

Consumers should note that flavoring agents like phenethyl butyrate are used in minimal quantities and contribute negligibly to overall dietary intake of their component chemicals.

Frequently Asked Questions

What is Phenethyl Butyrate?

Phenethyl butyrate is an organic compound (CAS 103-52-6) used as a flavoring agent in food products to impart fruity, berry-like sensory characteristics. It occurs naturally in some fruits and is synthesized for use in beverages, confections, and other flavored foods.

Is Phenethyl Butyrate safe?

Phenethyl Butyrate is currently rated "safe" based on FDA and EFSA data. It is approved in the US and not_evaluated in the EU. There are 0 FDA adverse event reports associated with this additive.

Is Phenethyl Butyrate banned in any country?

Phenethyl Butyrate is approved in the United States and not_evaluated in the European Union. Review the regulatory status cards above for the most current information.

Data Sources

Data is sourced exclusively from official government databases and updated periodically. This page does not constitute medical advice. Consult a healthcare professional for dietary guidance.