Our Verdict: RATING UNKNOWN

N-(heptan-4-yl)benzo[d][1,3]dioxole-5-carboxamide

CAS745047-51-2

Insufficient data to assign a rating

We do not have enough regulatory data to assign a safety rating to this additive at this time.

Adverse Events

0

FDA CFSAN

FDA Recalls

0

OpenFDA

United States

Approved

FDA

European Union

Not_evaluated

EFSA

N-(heptan-4-yl)benzo[d][1,3]dioxole-5-carboxamide — food additive

N-(heptan-4-yl)benzo[d][1,3]dioxole-5-carboxamide (CAS 745047-51-2) is a synthetic flavoring compound used to create specific taste and aroma profiles in food products. This benzodioxole derivative functions as a flavoring agent or adjuvant in the food industry.

US Status

Approved

FDA

EU Status

Not_evaluated

EFSA

Adverse Events

0

FDA CFSAN

FDA Recalls

0

OpenFDA

Global Regulatory Status

United States
ApprovedFDA
European Union
Not EvaluatedEFSA
United Kingdom
Not EvaluatedUK FSA
Canada
Not EvaluatedHealth Canada
Australia
Not EvaluatedFSANZ
Japan
Not EvaluatedMHLW
South Korea
Not EvaluatedMFDS
Brazil
Not EvaluatedANVISA
China
Not EvaluatedNHC / GB 2760
India
Not EvaluatedFSSAI
Country data is sourced from official regulatory databases and enriched via AI analysis. Always verify with the relevant national authority before making dietary decisions.

What is N-(heptan-4-yl)benzo[d][1,3]dioxole-5-carboxamide?

N-(heptan-4-yl)benzo[d][1,3]dioxole-5-carboxamide is a synthetic organic compound with the CAS number 745047-51-2. It belongs to the benzodioxole chemical family, characterized by a fused benzene and dioxole ring system. The compound features a heptan-4-yl (seven-carbon) side chain attached via an amide linkage. This specific molecular structure is designed to produce distinct sensory characteristics in food applications.

Common Uses

This flavoring agent is used in the food industry to enhance or modify taste and aroma profiles in various food products. As a flavoring adjuvant, it may be incorporated into beverages, confectionery, baked goods, dairy products, and other processed foods in small concentrations. The compound's specific chemical properties allow it to contribute particular flavor notes that manufacturers seek to achieve in their formulations. The actual prevalence of this ingredient in consumer products remains limited, as it represents a specialized flavoring option within the broader category of synthetic flavor compounds.

Safety Assessment

According to available FDA records, there have been zero reported adverse events associated with N-(heptan-4-yl)benzo[d][1,3]dioxole-5-carboxamide and zero recalls linked to this substance. The absence of adverse event reports and recalls suggests that products containing this compound have not generated safety concerns significant enough to warrant regulatory action or consumer complaints documented with the FDA.

It is important to note that this additive has not received FDA GRAS (Generally Recognized As Safe) status. This designation does not automatically indicate a safety concern; rather, it reflects that the compound either has not undergone the formal GRAS notification process or lacks sufficient data in the published literature to support such a determination. Many specialized or newly developed flavoring agents operate in this status category while maintaining acceptable safety profiles when used as intended.

The benzodioxole chemical class has a varied safety history. While some benzodioxole derivatives have been extensively studied and deemed safe at appropriate use levels, others in this chemical family have raised toxicological concerns. Regulatory agencies typically evaluate each compound individually based on its unique molecular structure, metabolic pathway, toxicological profile, and intended use level.

Regulatory Status

N-(heptan-4-yl)benzo[d][1,3]dioxole-5-carboxamide is not listed on the FDA's GRAS substance list. In the United States, flavoring agents can be used under FDA regulations without explicit GRAS approval if they comply with 21 CFR Part 182 or other applicable regulations, though GRAS status provides additional regulatory clarity and acceptance.

The regulatory status of this compound in other jurisdictions, including the European Union, may differ. The European Food Safety Authority (EFSA) maintains separate evaluations for flavoring substances. Manufacturers seeking to use this ingredient in different regulatory regions must comply with local flavor substance regulations and approval processes.

Key Studies

Published scientific literature on N-(heptan-4-yl)benzo[d][1,3]dioxole-5-carboxamide appears limited in the public domain. The compound represents a specialized synthetic flavoring with a narrower application scope compared to more widely used flavor ingredients. Most information regarding its safety and functional properties would typically reside in proprietary industry databases, manufacturer technical documentation, and regulatory submission files rather than peer-reviewed publications.

For compounds with limited published safety data, regulatory decisions often rely on submission dossiers from manufacturers that include toxicological testing, chemical characterization, and usage level justifications submitted directly to regulatory agencies. The absence of adverse events and recalls in FDA records provides some practical safety indication for products already in commerce.

Frequently Asked Questions

What is N-(heptan-4-yl)benzo[d][1,3]dioxole-5-carboxamide?

N-(heptan-4-yl)benzo[d][1,3]dioxole-5-carboxamide (CAS 745047-51-2) is a synthetic flavoring compound used to create specific taste and aroma profiles in food products. This benzodioxole derivative functions as a flavoring agent or adjuvant in the food industry.

Is N-(heptan-4-yl)benzo[d][1,3]dioxole-5-carboxamide safe?

N-(heptan-4-yl)benzo[d][1,3]dioxole-5-carboxamide is currently rated "unknown" based on FDA and EFSA data. It is approved in the US and not_evaluated in the EU. There are 0 FDA adverse event reports associated with this additive.

Is N-(heptan-4-yl)benzo[d][1,3]dioxole-5-carboxamide banned in any country?

N-(heptan-4-yl)benzo[d][1,3]dioxole-5-carboxamide is approved in the United States and not_evaluated in the European Union. Review the regulatory status cards above for the most current information.

Data Sources

Data is sourced exclusively from official government databases and updated periodically. This page does not constitute medical advice. Consult a healthcare professional for dietary guidance.