Our Verdict: RATING UNKNOWN

Isopropenyl Acetate

CAS108-22-5

Insufficient data to assign a rating

We do not have enough regulatory data to assign a safety rating to this additive at this time.

Adverse Events

0

FDA CFSAN

FDA Recalls

0

OpenFDA

United States

Approved

FDA

European Union

Not_evaluated

EFSA

Isopropenyl Acetate — food additive

Isopropenyl acetate (CAS 108-22-5) is a volatile organic compound used as a flavoring agent in food products. It contributes fruity and floral aromatic notes to various beverages and food formulations.

US Status

Approved

FDA

EU Status

Not_evaluated

EFSA

Adverse Events

0

FDA CFSAN

FDA Recalls

0

OpenFDA

Global Regulatory Status

United States
ApprovedFDA
European Union
Not EvaluatedEFSA
United Kingdom
Not EvaluatedUK FSA
Canada
Not EvaluatedHealth Canada
Australia
Not EvaluatedFSANZ
Japan
Not EvaluatedMHLW
South Korea
Not EvaluatedMFDS
Brazil
Not EvaluatedANVISA
China
Not EvaluatedNHC / GB 2760
India
Not EvaluatedFSSAI
Country data is sourced from official regulatory databases and enriched via AI analysis. Always verify with the relevant national authority before making dietary decisions.

What is Isopropenyl Acetate?

Isopropenyl acetate is an organic ester compound with the chemical formula C5H8O2. It exists as a colorless liquid with a fruity odor at room temperature. The compound is produced through chemical synthesis and belongs to the family of acetate esters commonly used in the flavor industry. Its volatile nature makes it particularly useful for imparting aromatic characteristics to food and beverage products.

Common Uses

Isopropenyl acetate functions primarily as a flavoring agent in the food industry. It is employed to create or enhance fruity and floral flavor profiles in various products, including beverages, confectionery, baked goods, and dairy products. As a volatile compound, it contributes mainly to the aromatic perception rather than taste, working synergistically with other flavor components to achieve desired sensory characteristics. The compound's use remains relatively specialized within the broader flavoring industry.

Safety Assessment

According to FDA records, there have been zero adverse events and zero recalls associated with isopropenyl acetate. The compound has not received GRAS (Generally Recognized As Safe) status from the FDA, which indicates it has not undergone the formal petition process for safety affirmation, though this does not necessarily indicate a safety concern. The absence of adverse event reports and recalls suggests no documented safety incidents in commercial food applications.

Toxicological data on isopropenyl acetate is limited in published literature available to consumers. Like many flavor compounds, safety assessments typically evaluate acute toxicity, irritation potential, and metabolic fate. The volatile nature of the compound means minimal systemic exposure would occur from typical food consumption. Industrial safety data suggests the compound should be handled with appropriate ventilation due to its volatile properties.

Regulatory Status

Isopropenyl acetate is not listed as GRAS by the FDA, meaning it does not have blanket approval for all food uses. However, its use in flavoring applications may be permitted under specific regulatory frameworks that allow use of certain flavoring substances. The FDA maintains regulations governing flavoring agents through 21 CFR Part 182, which establishes permitted uses for various flavor compounds. Manufacturers using isopropenyl acetate must ensure compliance with applicable regulations and labeling requirements in their jurisdiction.

In the European Union, flavoring regulations under Regulation (EC) No 1334/2008 govern the use of flavor compounds. The regulatory status may differ between jurisdictions, and manufacturers must verify compliance with local regulations before marketing products containing this ingredient.

Key Studies

Published scientific literature specifically evaluating isopropenyl acetate's safety profile in food applications is limited. Most safety information derives from general toxicological studies of structurally similar acetate esters and industrial safety data rather than food-specific research. The lack of extensive published studies reflects the compound's specialized use within the flavor industry rather than widespread application across food categories.

Research on related acetate esters has generally demonstrated low toxicity profiles when used in flavoring concentrations. The volatile and transient nature of such compounds typically results in minimal systemic absorption from food consumption. Additional research specific to isopropenyl acetate's flavor application would provide more comprehensive safety data, though the absence of adverse events in commercial use suggests acceptable safety margins at intended use levels.

Frequently Asked Questions

What is Isopropenyl Acetate?

Isopropenyl acetate (CAS 108-22-5) is a volatile organic compound used as a flavoring agent in food products. It contributes fruity and floral aromatic notes to various beverages and food formulations.

Is Isopropenyl Acetate safe?

Isopropenyl Acetate is currently rated "unknown" based on FDA and EFSA data. It is approved in the US and not_evaluated in the EU. There are 0 FDA adverse event reports associated with this additive.

Is Isopropenyl Acetate banned in any country?

Isopropenyl Acetate is approved in the United States and not_evaluated in the European Union. Review the regulatory status cards above for the most current information.

Data Sources

Data is sourced exclusively from official government databases and updated periodically. This page does not constitute medical advice. Consult a healthcare professional for dietary guidance.