Our Verdict: RATING UNKNOWN

Ethyl Vanillin Propylene Glycol Acetal

E-numberE1520CAS68527-76-4

Insufficient data to assign a rating

We do not have enough regulatory data to assign a safety rating to this additive at this time.

Adverse Events

0

FDA CFSAN

FDA Recalls

0

OpenFDA

United States

Approved

FDA

European Union

Not_evaluated

EFSA

Ethyl Vanillin Propylene Glycol Acetal — food additive

Ethyl vanillin propylene glycol acetal (CAS 68527-76-4) is a synthetic flavoring agent used to provide vanilla and vanillin notes in food products. It combines ethyl vanillin with propylene glycol in an acetal structure to create a stable, flavoring compound for use in various food applications.

US Status

Approved

FDA

EU Status

Not_evaluated

EFSA

Adverse Events

0

FDA CFSAN

FDA Recalls

0

OpenFDA

Global Regulatory Status

United States
ApprovedFDA
European Union
Not EvaluatedEFSA
United Kingdom
Not EvaluatedUK FSA
Canada
Not EvaluatedHealth Canada
Australia
Not EvaluatedFSANZ
Japan
Not EvaluatedMHLW
South Korea
Not EvaluatedMFDS
Brazil
Not EvaluatedANVISA
China
Not EvaluatedNHC / GB 2760
India
Not EvaluatedFSSAI
Country data is sourced from official regulatory databases and enriched via AI analysis. Always verify with the relevant national authority before making dietary decisions.

What is Ethyl Vanillin Propylene Glycol Acetal?

Ethyl vanillin propylene glycol acetal is a synthetic flavoring ingredient created by combining ethyl vanillin (a synthetic vanilla flavoring) with propylene glycol through an acetal chemical linkage. The acetal structure—formed when an aldehyde or ketone reacts with an alcohol—creates a more stable compound than ethyl vanillin alone. This stability can be advantageous in food manufacturing, as it may help preserve the vanilla flavor profile during processing, storage, and shelf life.

Ethyl vanillin itself is structurally similar to vanillin, the primary flavor compound in natural vanilla, but is entirely synthetic. The propylene glycol component serves as a solvent and stabilizing agent, helping to maintain the flavoring compound's integrity in food matrices.

Common Uses

As a flavoring agent, ethyl vanillin propylene glycol acetal is used in food products where vanilla or vanillin notes are desired. Typical applications may include:

- Baked goods and desserts

- Confectionery and candy products

- Beverages

- Dairy products such as ice cream and yogurt

- Processed snack foods

- Flavor compounds in food manufacturing

The concentration used in food products is typically very low, measured in parts per million (ppm), as flavoring agents are potent and only small quantities are needed to achieve the desired sensory effect.

Safety Assessment

Ethyl vanillin propylene glycol acetal has not been assigned GRAS (Generally Recognized as Safe) status by the FDA. However, this designation does not indicate that the additive is unsafe; rather, it means the manufacturer has not submitted a formal GRAS notification to the FDA, or that the FDA has not made a determination on such a submission.

Key safety considerations include:

**Adverse Event Reports**: The FDA has received zero adverse event reports associated with this additive, suggesting no documented harmful effects from consumer exposure.

**Recall History**: No FDA recalls involving this specific additive have been recorded, indicating no documented safety incidents severe enough to warrant market withdrawal.

**Component Safety**: Both ethyl vanillin and propylene glycol have extensive safety histories in food applications. Ethyl vanillin is similar to vanillin and is used as a flavoring agent in many countries. Propylene glycol is widely used as a solvent and humectant in food, pharmaceuticals, and cosmetics, with a well-established safety profile.

**Acetal Chemistry**: Acetals formed from food-grade components are generally considered stable and do not break down into harmful compounds under normal food storage conditions.

Regulatory Status

In the United States, this additive is not listed as GRAS by the FDA. It may be used in foods under FDA regulations for food additives, subject to specific limitations and approval. The exact regulatory pathway and use permissions may vary depending on the food category and intended use level.

International regulatory status may differ. Some countries may have different approval statuses or use restrictions. Manufacturers exporting products containing this ingredient should verify compliance with regulations in target markets.

Key Studies

Scientific literature specifically on ethyl vanillin propylene glycol acetal is limited, as it is a relatively specialized industrial flavoring ingredient. Safety assessments typically rely on:

- General toxicology data for ethyl vanillin

- Safety data for propylene glycol in food applications

- Stability and degradation studies for acetal-based flavorings

- Historical use data in food manufacturing

The absence of published adverse events or regulatory actions suggests this compound has not raised safety concerns in use. However, comprehensive toxicological studies specific to this acetal derivative may not be publicly available or may be proprietary to manufacturers.

Frequently Asked Questions

What is Ethyl Vanillin Propylene Glycol Acetal?

Ethyl vanillin propylene glycol acetal (CAS 68527-76-4) is a synthetic flavoring agent used to provide vanilla and vanillin notes in food products. It combines ethyl vanillin with propylene glycol in an acetal structure to create a stable, flavoring compound for use in various food applications.

Is Ethyl Vanillin Propylene Glycol Acetal safe?

Ethyl Vanillin Propylene Glycol Acetal is currently rated "unknown" based on FDA and EFSA data. It is approved in the US and not_evaluated in the EU. There are 0 FDA adverse event reports associated with this additive.

Is Ethyl Vanillin Propylene Glycol Acetal banned in any country?

Ethyl Vanillin Propylene Glycol Acetal is approved in the United States and not_evaluated in the European Union. Review the regulatory status cards above for the most current information.

Data Sources

Data is sourced exclusively from official government databases and updated periodically. This page does not constitute medical advice. Consult a healthcare professional for dietary guidance.