Our Verdict: SAFE

Cinnamaldehyde Propyleneglycol Acetal

CAS4353-01-9

This additive is considered safe

Based on current FDA and EFSA assessments. Approved in both the United States and the European Union.

Adverse Events

0

FDA CFSAN

FDA Recalls

0

OpenFDA

United States

Approved

FDA

European Union

Not_evaluated

EFSA

Cinnamaldehyde Propyleneglycol Acetal — food additive

Cinnamaldehyde propyleneglycol acetal is a synthetic flavoring compound derived from cinnamaldehyde, the primary component responsible for cinnamon's distinctive taste and aroma. It is used in food and beverage products to impart cinnamon-like flavoring.

US Status

Approved

FDA

EU Status

Not_evaluated

EFSA

Adverse Events

0

FDA CFSAN

FDA Recalls

0

OpenFDA

Global Regulatory Status

United States
ApprovedFDA
European Union
Not EvaluatedEFSA
United Kingdom
Not EvaluatedUK FSA
Canada
Not EvaluatedHealth Canada
Australia
Not EvaluatedFSANZ
Japan
Not EvaluatedMHLW
South Korea
Not EvaluatedMFDS
Brazil
Not EvaluatedANVISA
China
Not EvaluatedNHC / GB 2760
India
Not EvaluatedFSSAI
Country data is sourced from official regulatory databases and enriched via AI analysis. Always verify with the relevant national authority before making dietary decisions.

What is Cinnamaldehyde Propyleneglycol Acetal?

Cinnamaldehyde propyleneglycol acetal (CAS Number: 4353-01-9) is a synthetic organic compound created by reacting cinnamaldehyde with propylene glycol. Cinnamaldehyde is a naturally occurring aldehyde found in cinnamon bark and is responsible for cinnamon's characteristic spicy, warm flavor profile. The propylene glycol acetal formation is a chemical modification that stabilizes and preserves the flavoring compound, making it more suitable for use in processed foods and beverages.

Common Uses

This flavoring agent is primarily used in the food and beverage industry to provide cinnamon flavoring to various products. Common applications include:

- Baked goods and pastries

- Beverages including soft drinks and coffee products

- Confectionery and candy products

- Flavored dairy products

- Spice blends and seasonings

- Pharmaceutical and supplement formulations

The acetal form offers advantages over natural cinnamaldehyde in terms of stability, shelf life, and consistency in food applications. It allows manufacturers to maintain uniform flavor profiles across production batches.

Safety Assessment

Cinnamaldehyde propyleneglycol acetal has not been formally affirmed as Generally Recognized as Safe (GRAS) by the FDA. However, the FDA database shows zero reported adverse events and zero recalls associated with this additive, indicating a favorable safety profile in current use.

Both of its primary components have established safety histories. Propylene glycol is widely used in food and pharmaceutical products and is recognized as generally safe. Cinnamaldehyde has a long history of use as a spice and flavoring agent. The combination in acetal form represents a stable, non-reactive compound designed for flavoring purposes.

Cinnamaldehyde compounds in high concentrations have been studied for potential sensory irritation, but typical flavoring levels in food products are well below concentrations that would trigger such effects. Propylene glycol acetals are chemically inert and are not metabolically activated in the body.

Regulatory Status

In the United States, cinnamaldehyde propyleneglycol acetal is used as a flavoring agent under the regulatory framework for food additives. While it does not have explicit GRAS status from the FDA, it may be used in food under FDA regulations if the manufacturer can document its safety for the intended use, or it may be considered generally recognized as safe based on prior sanction or grandfather status.

The European Union maintains its own flavor compound regulations through the Flavor Regulation (EC) No 1334/2008. Cinnamaldehyde compounds are evaluated for safety through the European Flavour and Extract Manufacturers Association (EFEMA) processes.

Manufacturers using this compound must follow Good Manufacturing Practices and use it in levels that do not exceed those needed to achieve the intended flavoring effect.

Key Studies

While specific published studies on cinnamaldehyde propyleneglycol acetal are limited, the safety profile is supported by decades of research on both parent compounds. Cinnamaldehyde has been extensively studied for its flavor properties and safety in food applications. Propylene glycol acetal compounds are recognized as chemically stable, non-toxic compounds suitable for food use.

The absence of reported adverse events and recalls in FDA databases, combined with the established safety of component compounds and decades of use, suggests this additive can be considered safe when used as intended for flavoring purposes. As with all food additives, use should be consistent with Good Manufacturing Practices and established usage levels.

Frequently Asked Questions

What is Cinnamaldehyde Propyleneglycol Acetal?

Cinnamaldehyde propyleneglycol acetal is a synthetic flavoring compound derived from cinnamaldehyde, the primary component responsible for cinnamon's distinctive taste and aroma. It is used in food and beverage products to impart cinnamon-like flavoring.

Is Cinnamaldehyde Propyleneglycol Acetal safe?

Cinnamaldehyde Propyleneglycol Acetal is currently rated "safe" based on FDA and EFSA data. It is approved in the US and not_evaluated in the EU. There are 0 FDA adverse event reports associated with this additive.

Is Cinnamaldehyde Propyleneglycol Acetal banned in any country?

Cinnamaldehyde Propyleneglycol Acetal is approved in the United States and not_evaluated in the European Union. Review the regulatory status cards above for the most current information.

Data Sources

Data is sourced exclusively from official government databases and updated periodically. This page does not constitute medical advice. Consult a healthcare professional for dietary guidance.