Our Verdict: SAFE

Ascorbyl Stearate

E-numberE304CAS25395-66-8FDA GRAS

This additive is considered safe

Based on current FDA and EFSA assessments. Approved in both the United States and the European Union.

Adverse Events

0

FDA CFSAN

FDA Recalls

0

OpenFDA

United States

Approved

FDA

European Union

Not_evaluated

EFSA

Ascorbyl Stearate — food additive

Ascorbyl stearate is a fat-soluble derivative of vitamin C used as an antioxidant in food products. It prevents oxidation and rancidity in foods containing fats and oils, extending shelf life while maintaining nutritional quality.

US Status

Approved

FDA

EU Status

Not_evaluated

EFSA

Adverse Events

0

FDA CFSAN

FDA Recalls

0

OpenFDA

Global Regulatory Status

United States
ApprovedFDA
European Union
Not EvaluatedEFSA
United Kingdom
Not EvaluatedUK FSA
Canada
ApprovedHealth Canada
Australia
Not EvaluatedFSANZ
Japan
Not EvaluatedMHLW
South Korea
Not EvaluatedMFDS
Brazil
Not EvaluatedANVISA
China
Not EvaluatedNHC / GB 2760
India
Not EvaluatedFSSAI
Country data is sourced from official regulatory databases and enriched via AI analysis. Always verify with the relevant national authority before making dietary decisions.

What is Ascorbyl Stearate?

Ascorbyl stearate (CAS Number: 25395-66-8) is a chemical compound formed by esterifying ascorbic acid (vitamin C) with stearic acid, a naturally occurring saturated fatty acid. This modification makes ascorbic acid fat-soluble, allowing it to function effectively in lipid-rich food environments where water-soluble vitamin C would be ineffective. The compound appears as a white to off-white powder and is valued in food manufacturing for its dual role as both a preservative and a source of vitamin C activity.

Common Uses

Ascorbyl stearate is primarily used in processed foods containing fats and oils where oxidation poses a preservation challenge. Common applications include:

- Baked goods and bread products

- Processed meats and cured meat products

- Vegetable oils and shortenings

- Dry soup mixes and instant foods

- Cosmetic and personal care formulations

- Dietary supplements

The additive functions by donating electrons to free radicals, neutralizing them before they can initiate the oxidation chain reaction that leads to rancidity, color degradation, and loss of nutritional value. This makes it particularly useful in products with extended shelf lives or those exposed to heat, light, or oxygen during storage.

Safety Assessment

Ascorbyl stearate has been evaluated extensively for safety in food applications. The FDA has granted it Generally Recognized as Safe (GRAS) status, indicating that qualified experts consider it safe for its intended use based on scientific literature and historical consumption data. The GRAS determination reflects that the compound poses no known safety concerns at levels used in food.

The FDA maintains a searchable adverse event database for food additives. As of current records, ascorbyl stearate has zero documented adverse events reported through FDA channels and zero product recalls associated with its use. This lack of reported incidents, combined with its GRAS status, indicates a strong safety profile in practical food applications.

Because ascorbyl stearate is derived from ascorbic acid (vitamin C), a nutrient essential for human health, and stearic acid, a common dietary fatty acid, the compound breaks down in the body through normal metabolic pathways. Toxicological studies have not identified concerns regarding accumulation or systemic toxicity.

Regulatory Status

Ascorbyl stearate is approved for use in food applications under FDA regulations (21 CFR 182.3013) and is classified as a direct human food additive. The European Food Safety Authority (EFSA) has also evaluated ascorbyl stearate and permits its use in food products across European Union member states.

Regulatory agencies set maximum use levels for ascorbyl stearate based on technological necessity and safety margins. Manufacturers must follow labeling requirements and use the additive only in amounts needed to achieve its preservative function. The compound is recognized internationally in food safety standards and appears in the Codex Alimentarius general standards for food additives.

Key Studies

Scientific literature supports the safety of ascorbyl stearate through multiple research pathways. Bioavailability studies demonstrate that the compound is hydrolyzed in the gastrointestinal tract, releasing ascorbic acid and stearic acid, both of which are normal dietary components metabolized through established biochemical pathways.

Toxicological studies in animal models have established safety margins well above expected human dietary exposure levels. Acute and subchronic toxicity testing has not revealed target organ toxicity or systemic effects at relevant doses.

The GRAS determination itself represents a comprehensive evaluation of available scientific data, including microbial analysis, chemical composition verification, and review of historical safety records. This determination undergoes periodic review as new scientific information becomes available.

Frequently Asked Questions

What is Ascorbyl Stearate?

Ascorbyl stearate is a fat-soluble derivative of vitamin C used as an antioxidant in food products. It prevents oxidation and rancidity in foods containing fats and oils, extending shelf life while maintaining nutritional quality.

Is Ascorbyl Stearate safe?

Ascorbyl Stearate is currently rated "safe" based on FDA and EFSA data. It is approved in the US and not_evaluated in the EU. There are 0 FDA adverse event reports associated with this additive.

Is Ascorbyl Stearate banned in any country?

Ascorbyl Stearate is approved in the United States and not_evaluated in the European Union. Review the regulatory status cards above for the most current information.

Data Sources

Data is sourced exclusively from official government databases and updated periodically. This page does not constitute medical advice. Consult a healthcare professional for dietary guidance.