Our Verdict: RATING UNKNOWN

Aconitic Acid

CAS499-12-7

Insufficient data to assign a rating

We do not have enough regulatory data to assign a safety rating to this additive at this time.

Adverse Events

0

FDA CFSAN

FDA Recalls

0

OpenFDA

United States

Approved

FDA

European Union

Not_evaluated

EFSA

Aconitic Acid — food additive

Aconitic acid (CAS 499-12-7) is an organic acid naturally found in plants, particularly in sugar cane and citrus fruits. It is used as a flavoring agent and flavor adjuvant in food products to enhance or modify taste profiles.

US Status

Approved

FDA

EU Status

Not_evaluated

EFSA

Adverse Events

0

FDA CFSAN

FDA Recalls

0

OpenFDA

Global Regulatory Status

United States
ApprovedFDA
European Union
Not EvaluatedEFSA
United Kingdom
UnknownUK FSA
Canada
UnknownHealth Canada
Australia
UnknownFSANZ
Japan
UnknownMHLW
South Korea
UnknownMFDS
Brazil
UnknownANVISA
China
UnknownNHC / GB 2760
India
UnknownFSSAI
Country data is sourced from official regulatory databases and enriched via AI analysis. Always verify with the relevant national authority before making dietary decisions.

What is Aconitic Acid?

Aconitic acid is a tricarboxylic organic acid with the molecular formula C₆H₆O₆. It occurs naturally in various plants, including sugar cane, citrus fruits, and other botanical sources. The compound exists in three isomeric forms: cis-aconitic acid and trans-aconitic acid being the most common. Aconitic acid is structurally related to citric acid and plays a role in plant metabolism, particularly in the citric acid cycle.

In food applications, aconitic acid functions as a flavoring agent and flavor adjuvant, contributing to the sensory profile of food and beverage products. Its acidic nature and subtle flavor characteristics make it useful in formulations where specific taste modifications are desired.

Common Uses

Aconitic acid is used in the food industry primarily as a flavor enhancer and acidifying agent. Its applications include beverages, confectionery, and processed food products where flavor modification or acidic taste profiles are desired. The compound's natural occurrence in foods means some products contain trace amounts from raw material sources.

Because aconitic acid occurs naturally in foods, particularly in citrus and other plant-based ingredients, consumers may be exposed to small quantities through normal dietary sources independent of intentional food additive use.

Safety Assessment

The safety profile of aconitic acid shows no reported adverse events in FDA databases and no associated recalls. The compound has not been formally classified as Generally Recognized As Safe (GRAS) by the FDA, which means it does not have blanket approval for use in all food categories.

Toxicological data on aconitic acid is limited compared to more widely used food additives. The acid's natural presence in foods and its metabolic similarities to other organic acids suggest a relatively low toxicity profile, though comprehensive human safety studies are not extensively documented in public literature.

As an organic acid, aconitic acid would be expected to have low systemic toxicity when ingested in the small quantities typical of food applications. Its role in plant metabolism and natural occurrence suggests biological compatibility with human consumption at dietary levels.

Regulatory Status

Aconitic acid does not have FDA GRAS status, indicating that while the FDA has not formally prohibited its use, it also has not received the blanket approval status that GRAS compounds enjoy. This means any use in food would require either GRAS notification support or would need to be evaluated on a case-by-case basis.

The lack of GRAS designation does not necessarily indicate safety concerns but rather reflects the limited formal regulatory review the compound has undergone compared to more established food additives. The absence of adverse events and recalls suggests no identified safety issues at current exposure levels.

Regulatory approaches to aconitic acid vary internationally. Some food regulatory frameworks may permit its use based on natural occurrence or specific approvals, while others maintain more restrictive positions pending additional safety documentation.

Key Studies

Published scientific literature on aconitic acid as a food additive is limited. Most available information derives from its natural occurrence in foods, botanical chemistry, and its role in plant metabolism rather than from dedicated safety studies as a food ingredient.

The absence of adverse event reports and recalls indicates no documented safety signals from food use. However, the limited scope of formal toxicological testing and the lack of comprehensive human exposure data means definitive safety conclusions depend on the assumed intake levels and intended applications.

Frequently Asked Questions

What is Aconitic Acid?

Aconitic acid (CAS 499-12-7) is an organic acid naturally found in plants, particularly in sugar cane and citrus fruits. It is used as a flavoring agent and flavor adjuvant in food products to enhance or modify taste profiles.

Is Aconitic Acid safe?

Aconitic Acid is currently rated "unknown" based on FDA and EFSA data. It is approved in the US and not_evaluated in the EU. There are 0 FDA adverse event reports associated with this additive.

Is Aconitic Acid banned in any country?

Aconitic Acid is approved in the United States and not_evaluated in the European Union. Review the regulatory status cards above for the most current information.

Data Sources

Data is sourced exclusively from official government databases and updated periodically. This page does not constitute medical advice. Consult a healthcare professional for dietary guidance.