What is 2,6,10-trimethyl-2,6,10-pentadecatrien-14-one?
2,6,10-trimethyl-2,6,10-pentadecatrien-14-one is a synthetic flavoring compound with the CAS number 762-29-8. This compound is a branched organic molecule containing multiple double bonds (pentadecatriene) and a ketone functional group. It falls under the broader category of flavor compounds that are engineered to replicate or enhance natural flavors in food and beverage products.
Common Uses
This flavoring agent is used in the food industry as a flavoring adjuvant, meaning it may be used to support, enhance, or modify the overall flavor profile of food products. Like many synthetic flavor compounds, it is typically used in very small quantities—often in parts per million (ppm)—to achieve the desired sensory effect. The compound may appear in various processed foods and beverages, though specific applications depend on regulatory approval in individual markets.
Safety Assessment
According to FDA records, there have been zero reported adverse events associated with this additive and zero recalls linked to its use. This lack of reported incidents suggests no documented safety concerns have emerged from its use in the food supply. However, the absence of adverse event reports does not constitute a formal safety approval by regulatory agencies.
The compound has not received FDA GRAS (Generally Recognized As Safe) status, which means it has not been formally evaluated and classified as safe by the FDA through standard review procedures. This status distinction is important: GRAS designation represents formal regulatory recognition, while lack of reported problems indicates practical safety experience. The presence of zero adverse events in FDA databases is consistent with safe use at the levels typically employed in food flavoring applications.
Regulatory Status
This additive is currently not on the FDA's GRAS list. However, the lack of GRAS status does not necessarily indicate safety concerns—it may reflect factors such as limited industry use, the specialized nature of its application, or the additive's market positioning. Different regulatory frameworks worldwide treat flavoring compounds with varying levels of stringency.
Flavor compounds are often regulated through different pathways than other food additives. The FDA maintains specific regulations for flavoring substances, and manufacturers using non-GRAS approved flavorings typically operate under specific authorization or petition processes. The zero adverse events and zero recalls associated with this compound suggest it has not posed compliance or safety problems in practice.
Key Studies
Limited published research specifically targeting this compound is readily available in open literature databases. Toxicological data for many synthetic flavor compounds is held by manufacturers and submitted to regulatory agencies as part of confidential submissions during approval processes. The safety assessment of flavoring agents typically relies on structural analysis, metabolism studies, and historical use data rather than extensive clinical trials.
For flavoring compounds of this type, safety evaluation generally considers: metabolic pathways, predicted human exposure levels, structural similarity to known safe compounds, and any available animal toxicity studies. The absence of adverse events in FDA databases provides practical confirmation that issues have not emerged during commercial use.
Manufacturers and regulatory bodies apply conservative principles to flavor safety, often setting permitted levels well below those calculated to produce any adverse effect. The continued use of this compound without reported safety incidents supports its continued classification as a functional flavoring agent.