Our Verdict: RATING UNKNOWN

2,4-hexadienyl Propionate

CAS16491-25-1

Insufficient data to assign a rating

We do not have enough regulatory data to assign a safety rating to this additive at this time.

Adverse Events

0

FDA CFSAN

FDA Recalls

0

OpenFDA

United States

Approved

FDA

European Union

Not_evaluated

EFSA

2,4-hexadienyl Propionate — food additive

2,4-hexadienyl Propionate (CAS 16491-25-1) is a synthetic flavoring compound used to impart fruity and floral notes in food and beverage products. It functions as a flavoring agent or adjuvant in the food industry.

US Status

Approved

FDA

EU Status

Not_evaluated

EFSA

Adverse Events

0

FDA CFSAN

FDA Recalls

0

OpenFDA

Global Regulatory Status

United States
ApprovedFDA
European Union
Not EvaluatedEFSA
United Kingdom
Not EvaluatedUK FSA
Canada
Not EvaluatedHealth Canada
Australia
Not EvaluatedFSANZ
Japan
Not EvaluatedMHLW
South Korea
Not EvaluatedMFDS
Brazil
Not EvaluatedANVISA
China
Not EvaluatedNHC / GB 2760
India
Not EvaluatedFSSAI
Country data is sourced from official regulatory databases and enriched via AI analysis. Always verify with the relevant national authority before making dietary decisions.

What is 2,4-hexadienyl Propionate?

2,4-hexadienyl Propionate is a synthetic organic compound classified as a flavoring agent. It belongs to the ester family of flavor compounds, characterized by a propionic acid moiety attached to a 2,4-hexadienyl group. This molecular structure gives it distinctive aromatic properties that food manufacturers utilize to create or enhance specific taste profiles in consumer products.

Common Uses

2,4-hexadienyl Propionate is used primarily in the flavor industry as a flavoring agent or adjuvant. Like other synthetic flavor compounds, it appears in formulations for beverages, confectionery, baked goods, and dairy products where fruity or floral flavor notes are desired. The compound contributes to the sensory profile of finished food products, often in combination with other flavoring agents rather than as a standalone ingredient.

As a flavoring adjuvant, it may also serve supportive functions in flavor formulations, helping to stabilize or modulate other flavor components. Typical use levels in food applications are measured in parts per million (ppm), reflecting the potency of synthetic flavor compounds.

Safety Assessment

The safety profile of 2,4-hexadienyl Propionate appears limited in publicly available literature. The FDA has not designated this compound as Generally Recognized as Safe (GRAS), indicating it has not undergone the formal GRAS notification process or did not receive GRAS determination through that pathway. However, the absence of GRAS status does not necessarily indicate safety concerns; rather, it reflects the regulatory classification pathway chosen by manufacturers.

According to FDA records, there are zero reported adverse events associated with this additive and zero recalls involving 2,4-hexadienyl Propionate. This absence of adverse event reports suggests no documented consumer health complaints or safety incidents linked to its use in food.

As a synthetic flavor compound, 2,4-hexadienyl Propionate operates under the broader regulatory framework for flavoring substances. In the United States, flavoring agents are generally subject to FDA regulations that require their safety for intended use before market introduction. The European Food Safety Authority (EFSA) maintains separate evaluations of flavoring substances in EU jurisdictions.

Regulatory Status

In the United States, 2,4-hexadienyl Propionate is not listed as a GRAS substance, meaning it may be used in food products under the Food Additive Amendment if appropriate regulatory provisions exist, or it may fall under established flavor ingredient regulations. Food manufacturers must ensure compliance with FDA requirements for any additive used in their products.

The compound's regulatory status may vary internationally. Different countries maintain separate approval lists for flavoring substances, and approval in one jurisdiction does not automatically confer approval in others. Manufacturers seeking to use this ingredient globally must verify its regulatory status in each target market.

Key Studies

Publicly available toxicological or safety studies specifically examining 2,4-hexadienyl Propionate are limited in the scientific literature. The lack of prominent published research may reflect the specialized nature of flavoring compound safety assessment, which is often conducted through confidential industry channels or proprietary databases rather than published peer-reviewed studies.

General safety principles for synthetic flavor compounds involve assessment of absorption, metabolism, and potential toxicity at expected dietary exposure levels. For minor flavor components used at low concentrations (typically ppm levels), the margin of safety often remains substantial relative to no-observed-adverse-effect-level (NOAEL) determinations.

Consumers seeking additional information about specific product formulations containing this ingredient should contact manufacturers directly, as ingredient levels and safety documentation may not be publicly disclosed.

Frequently Asked Questions

What is 2,4-hexadienyl Propionate?

2,4-hexadienyl Propionate (CAS 16491-25-1) is a synthetic flavoring compound used to impart fruity and floral notes in food and beverage products. It functions as a flavoring agent or adjuvant in the food industry.

Is 2,4-hexadienyl Propionate safe?

2,4-hexadienyl Propionate is currently rated "unknown" based on FDA and EFSA data. It is approved in the US and not_evaluated in the EU. There are 0 FDA adverse event reports associated with this additive.

Is 2,4-hexadienyl Propionate banned in any country?

2,4-hexadienyl Propionate is approved in the United States and not_evaluated in the European Union. Review the regulatory status cards above for the most current information.

Data Sources

Data is sourced exclusively from official government databases and updated periodically. This page does not constitute medical advice. Consult a healthcare professional for dietary guidance.