(2,4)- And (3,5)- And (3,6)-dimethyl-3-cyclohexenylcarbaldehyde

(2,4)- and (3,5)- and (3,6)-dimethyl-3-cyclohexenylcarbaldehyde (CAS Number 27939-60-2) is a synthetic organic compound belonging to the aldehyde class of flavor chemicals. The additive exists as a mixture of three structural isomers, each containing a cyclohexene ring with two methyl substituents and an aldehyde functional group. This chemical structure contributes to its characteristic woody, floral, and slightly spicy aromatic profile.

This flavoring agent is utilized in the formulation of food and beverage products where woody and floral flavor notes are desired. It is employed in various categories including alcoholic beverages, non-alcoholic drinks, baked goods, confectionery, and savory food products. The compound functions at very low concentrations, typically in the parts-per-million range, where its sensory contribution is most effective. Like other synthetic flavor chemicals, it allows manufacturers to achieve consistent flavor profiles across production batches.

The compound has not been formally evaluated and approved by the FDA as a Generally Recognized As Safe (GRAS) substance. However, it remains available for use under FDA regulations governing flavor additives. The FDA's database contains zero reported adverse events associated with this additive, and no recalls have been issued relating to its use. This absence of reported safety incidents, combined with its authorization for food use, suggests no significant acute safety concerns at typical use levels.

As with other synthetic flavor aldehydes, the safety profile is based on the principle that flavoring agents are used at extremely low concentrations. The lethal dose or toxic threshold would typically be orders of magnitude higher than exposure levels from food consumption. The aldehyde functional group is common to many naturally-occurring and approved flavor compounds, such as cinnamaldehyde and benzaldehyde.

While not GRAS-affirmed, this additive is permitted for use as a flavoring agent under FDA regulations 21 CFR Part 182 and related flavor regulations. It may be subject to different regulatory classifications in other countries. The European Union and other regulatory bodies maintain separate evaluations of flavor chemicals, and approval status may vary by jurisdiction. Manufacturers using this ingredient should verify compliance with regulations in all markets where products are distributed.

The lack of GRAS status does not indicate safety concerns; rather, it reflects that formal GRAS determination petitions have not been submitted to the FDA or that industry has determined alternative regulatory pathways are more appropriate for this ingredient.

Limited published scientific literature specifically addresses this particular isomer mixture. The structural similarity to other approved aldehyde flavoring agents suggests comparable metabolic pathways and safety profiles. Aldehydes of similar structure have been studied for their sensory properties and flavor thresholds in food applications. The extremely low use concentrations (typically less than 50 ppm in finished products) further minimize potential exposure concerns.

Regulatory acceptance of this ingredient across multiple food product categories implies acceptable safety margins when used according to industry practice and good manufacturing guidelines. Ongoing monitoring through FDA's adverse event reporting system provides post-market surveillance for any emerging safety signals.