Our Verdict: USE WITH CAUTION

Nickel

CAS7440-02-0

Some regulatory concerns have been raised

This additive has been flagged by at least one major regulatory agency or peer-reviewed study. Review the evidence below before forming conclusions.

Adverse Events

0

FDA CFSAN

FDA Recalls

0

OpenFDA

United States

Approved

FDA

European Union

Not_evaluated

EFSA

Nickel — food additive

Nickel (CAS 7440-02-0) is a naturally occurring metallic element that may be present in food as a processing aid or contaminant. It is not intentionally added to foods as a direct ingredient but can be introduced through food processing equipment and contact surfaces.

US Status

Approved

FDA

EU Status

Not_evaluated

EFSA

Adverse Events

0

FDA CFSAN

FDA Recalls

0

OpenFDA

Global Regulatory Status

United States
ApprovedFDA
European Union
Not EvaluatedEFSA
United Kingdom
UnknownUK FSA
Canada
UnknownHealth Canada
Australia
UnknownFSANZ
Japan
UnknownMHLW
South Korea
UnknownMFDS
Brazil
UnknownANVISA
China
UnknownNHC / GB 2760
India
UnknownFSSAI
Country data is sourced from official regulatory databases and enriched via AI analysis. Always verify with the relevant national authority before making dietary decisions.

What is Nickel?

Nickel is a naturally occurring metallic element with atomic number 28. In the context of food safety, nickel is not typically added as a direct food ingredient but rather functions as a processing aid through contact with food processing equipment, cookware, and food contact surfaces. Stainless steel equipment, which commonly contains nickel as an alloying element, is the primary source of nickel in processed foods. The metal is silvery-white, corrosion-resistant, and widely used in industrial applications including food manufacturing equipment.

Common Uses

Nickel's presence in food is primarily incidental rather than intentional. It appears in foods through:

- Stainless steel processing equipment and machinery used in food manufacturing

- Food contact surfaces in commercial and institutional kitchens

- Cookware and utensils used in food preparation

- Packaging materials that may contain nickel-containing alloys

Nickel may leach into foods, particularly acidic or high-salt foods, and alkaline foods during cooking or processing. The amount that migrates depends on factors including temperature, cooking time, food composition, and the condition of the equipment surface.

Safety Assessment

Nickel exposure through food is a recognized concern, particularly for individuals with nickel sensitivity or allergic contact dermatitis. The primary health concern related to nickel is sensitization and allergic reactions rather than acute toxicity from ingestion. Some individuals develop nickel allergy through repeated skin contact and may subsequently experience reactions to dietary nickel intake.

The International Agency for Research on Cancer (IARC) classifies nickel as a Group 1 carcinogen based on inhalation exposure in occupational settings, primarily affecting the respiratory system. However, this classification applies to nickel dust and fumes from occupational exposure, not dietary nickel from food contact.

The European Food Safety Authority (EFSA) has established a migration limit for nickel from food contact materials. The European Union sets a specific migration limit of 0.02 mg/dm² for nickel from ceramics and glass, and regulates nickel release from stainless steel equipment.

Dietary intake of nickel varies geographically and depends on local food sources. Some foods naturally contain higher nickel levels, including nuts, grains, legumes, and chocolate. The average dietary intake ranges from 70-100 micrograms per day in most populations.

Regulatory Status

Nickel is not approved as a food additive by the FDA and does not have GRAS (Generally Recognized As Safe) status as a direct food ingredient. The FDA regulates nickel under food contact substance regulations for equipment and cookware. The agency has not established specific maximum limits for nickel migration into food, instead relying on good manufacturing practices and material specifications.

The European Union has implemented specific migration limits for nickel from food contact materials, treating it as a regulated contaminant rather than an approved additive. This reflects a precautionary approach to metals in food contact.

No adverse events or recalls specifically attributed to nickel have been reported to the FDA, suggesting that current levels from food contact sources do not pose acute health risks to the general population.

Key Studies

Research on nickel in food has focused on migration studies from stainless steel equipment, dietary intake assessment, and health effects in sensitized individuals. Studies have demonstrated that acidic foods and prolonged cooking increase nickel migration from stainless steel cookware. Population-based studies have estimated safe intake levels for the general population while identifying individuals with nickel sensitivity as potentially requiring dietary management.

The lack of FDA adverse events or recalls related to nickel suggests current exposure levels through food contact are not causing measurable acute harm in the general population, though vulnerable individuals may need to minimize exposure.

Frequently Asked Questions

What is Nickel?

Nickel (CAS 7440-02-0) is a naturally occurring metallic element that may be present in food as a processing aid or contaminant. It is not intentionally added to foods as a direct ingredient but can be introduced through food processing equipment and contact surfaces.

Is Nickel safe?

Nickel is currently rated "caution" based on FDA and EFSA data. It is approved in the US and not_evaluated in the EU. There are 0 FDA adverse event reports associated with this additive.

Is Nickel banned in any country?

Nickel is approved in the United States and not_evaluated in the European Union. Review the regulatory status cards above for the most current information.

Data Sources

Data is sourced exclusively from official government databases and updated periodically. This page does not constitute medical advice. Consult a healthcare professional for dietary guidance.