Our Verdict: SAFE

Hydroxylated Lecithin

E-numberE322CAS8029-76-3FDA GRAS

This additive is considered safe

Based on current FDA and EFSA assessments. Approved in both the United States and the European Union.

Adverse Events

0

FDA CFSAN

FDA Recalls

0

OpenFDA

United States

Approved

FDA

European Union

Not_evaluated

EFSA

Hydroxylated Lecithin — food additive

Hydroxylated lecithin is a modified form of lecithin, a naturally-derived emulsifier produced by treating soy or sunflower lecithin with hydrogen. It is widely used in food manufacturing to improve texture, stability, and consistency in products ranging from chocolates to baked goods.

US Status

Approved

FDA

EU Status

Not_evaluated

EFSA

Adverse Events

0

FDA CFSAN

FDA Recalls

0

OpenFDA

Global Regulatory Status

United States
ApprovedFDA
European Union
Not EvaluatedEFSA
United Kingdom
Not EvaluatedUK FSA
Canada
ApprovedHealth Canada
Australia
Not EvaluatedFSANZ
Japan
Not EvaluatedMHLW
South Korea
Not EvaluatedMFDS
Brazil
Not EvaluatedANVISA
China
Not EvaluatedNHC / GB 2760
India
Not EvaluatedFSSAI
Country data is sourced from official regulatory databases and enriched via AI analysis. Always verify with the relevant national authority before making dietary decisions.

What is Hydroxylated Lecithin?

Hydroxylated lecithin (CAS Number 8029-76-3) is a chemically modified emulsifier derived from natural lecithin sources, primarily soy or sunflower. The hydroxylation process involves adding hydroxyl groups to lecithin molecules through controlled chemical treatment. This modification enhances the emulsifying properties of the base lecithin, making it more effective at lower concentrations and more stable across varying pH and temperature conditions.

Lecithin itself is a phospholipid naturally present in plant and animal tissues. The hydroxylation process creates a derivative with improved functional properties while maintaining its core emulsifying capabilities. The resulting additive is soluble in both aqueous and lipid phases, allowing it to effectively stabilize mixtures of oil and water that would otherwise separate.

Common Uses

Hydroxylated lecithin is used extensively in the food industry as an emulsifier and emulsifier salt. Common applications include:

- Chocolate and confectionery products, where it improves fluidity and texture

- Baked goods and bread products to enhance crumb structure and shelf life

- Dairy products and margarine formulations

- Convenience foods and prepared meals

- Nutritional supplements and fortified foods

- Cosmetic and pharmaceutical preparations

The additive typically functions at concentrations between 0.1% and 1% by weight, depending on the application and desired effect. Its ability to stabilize emulsions at lower usage rates compared to unmodified lecithin makes it economically efficient for manufacturers.

Safety Assessment

Hydroxylated lecithin has been extensively evaluated for safety. The FDA has granted it Generally Recognized as Safe (GRAS) status, indicating that qualified experts consider it safe for use in food under specified conditions. According to FDA records, there are zero adverse events associated with hydroxylated lecithin and zero product recalls linked to this ingredient.

The European Food Safety Authority (EFSA) has also reviewed lecithin and its derivatives favorably. The safety profile is well-established due to the long history of lecithin use in food manufacturing, dating back decades. The hydroxylation process itself does not introduce concerning toxicological properties.

Since lecithin is naturally present in foods and the hydroxylation process is a mild chemical modification, the modified form maintains a favorable safety profile. Studies have consistently shown no mutagenic, carcinogenic, or reproductive toxicity concerns at food-relevant exposure levels.

Regulatory Status

Hydroxylated lecithin is permitted for use in food across multiple regulatory jurisdictions:

- **United States**: FDA GRAS status allows use as a direct food additive without quantity restrictions in many applications

- **European Union**: Approved under Regulation (EC) No 1333/2008 as food additive E322 (lecithin and derivatives)

- **Canada**: Permitted as a food additive under the Food and Drugs Act

- **Australia/New Zealand**: Approved for various food categories under Food Standards Code

The regulatory acceptance reflects the substantial safety data and the ingredient's non-toxic profile demonstrated through both preclinical studies and decades of safe use in food.

Key Studies

Research on lecithin and hydroxylated lecithin has focused on its functional efficacy and safety. Key findings include:

- Studies confirm that hydroxylation enhances emulsifying efficiency, requiring lower application rates than native lecithin

- Gastrointestinal tolerance studies show no adverse effects from dietary consumption

- Stability studies demonstrate improved performance under various processing conditions

- Long-term safety data from regulatory submissions support GRAS determination

The scientific consensus supports hydroxylated lecithin as a safe and effective food additive when used according to regulatory guidelines. Ongoing monitoring through post-market surveillance systems continues to track safety profiles across multiple food categories.

Frequently Asked Questions

What is Hydroxylated Lecithin?

Hydroxylated lecithin is a modified form of lecithin, a naturally-derived emulsifier produced by treating soy or sunflower lecithin with hydrogen. It is widely used in food manufacturing to improve texture, stability, and consistency in products ranging from chocolates to baked goods.

Is Hydroxylated Lecithin safe?

Hydroxylated Lecithin is currently rated "safe" based on FDA and EFSA data. It is approved in the US and not_evaluated in the EU. There are 0 FDA adverse event reports associated with this additive.

Is Hydroxylated Lecithin banned in any country?

Hydroxylated Lecithin is approved in the United States and not_evaluated in the European Union. Review the regulatory status cards above for the most current information.

Data Sources

Data is sourced exclusively from official government databases and updated periodically. This page does not constitute medical advice. Consult a healthcare professional for dietary guidance.