Our Verdict: SAFE

Cottonseed Flour, Partially Defatted, Cooked

CAS977050-54-6

This additive is considered safe

Based on current FDA and EFSA assessments. Approved in both the United States and the European Union.

Adverse Events

0

FDA CFSAN

FDA Recalls

0

OpenFDA

United States

Approved

FDA

European Union

Not_evaluated

EFSA

Cottonseed Flour, Partially Defatted, Cooked — food additive

Cottonseed flour, partially defatted, cooked is a processed plant-derived ingredient made from cottonseed that has had most of its oil removed and been heat-treated. It functions as a processing aid in food manufacturing and is generally recognized as safe by food scientists, though it is not formally approved as GRAS by the FDA.

US Status

Approved

FDA

EU Status

Not_evaluated

EFSA

Adverse Events

0

FDA CFSAN

FDA Recalls

0

OpenFDA

Global Regulatory Status

United States
ApprovedFDA
European Union
Not EvaluatedEFSA
United Kingdom
Not EvaluatedUK FSA
Canada
Not EvaluatedHealth Canada
Australia
Not EvaluatedFSANZ
Japan
Not EvaluatedMHLW
South Korea
Not EvaluatedMFDS
Brazil
Not EvaluatedANVISA
China
Not EvaluatedNHC / GB 2760
India
Not EvaluatedFSSAI
Country data is sourced from official regulatory databases and enriched via AI analysis. Always verify with the relevant national authority before making dietary decisions.

What is Cottonseed Flour, Partially Defatted, Cooked?

Cottonseed flour, partially defatted, cooked is a processed ingredient derived from cottonseed (Gossypium species). The production process involves removing the seed coat, extracting most of the oil content (partial defating), and then applying heat treatment. The resulting product is a light-colored, fine powder with relatively low fat content compared to whole cottonseed flour. This ingredient is distinct from whole cottonseed flour due to its reduced lipid profile and thermal processing, which affects its functional properties in food systems.

Common Uses

Cottonseed flour functions primarily as a processing aid in food manufacturing rather than as a direct food ingredient or additive with functional properties like emulsification or thickening. Processing aids are substances used during manufacturing that may be removed before the final product reaches consumers, or if retained, are present in insignificant quantities. In industrial food production, cottonseed flour may be utilized in various applications where its protein content, fiber characteristics, or binding properties provide technical benefits during processing. It has historical use in certain food manufacturing contexts, though specific contemporary applications are limited.

Safety Assessment

Cottonseed has a long history of use in food and feed applications. The primary safety consideration historically associated with cottonseed is gossypol, a natural polyphenolic compound present in cottonseed that can have physiological effects at high levels. However, through the partial defating and cooking processes applied to this ingredient, gossypol levels are significantly reduced. The cooking process denatures proteins and may reduce certain antinutritional factors, contributing to improved safety and nutritional quality.

No adverse events related to cottonseed flour, partially defatted, cooked have been reported to the FDA. Additionally, no recalls involving this specific ingredient have been documented in FDA records, suggesting a history of safe use in food manufacturing. The absence of reported safety incidents, combined with the thermal processing that reduces natural toxicants, supports a favorable safety profile.

Individuals with cotton plant allergies are extremely rare, and allergic reactions to cottonseed products are uncommon. However, as with any plant-derived ingredient, theoretical allergenic potential exists, particularly in individuals with multiple seed allergies.

Regulatory Status

Cottonseed flour, partially defatted, cooked is not listed as a GRAS (Generally Recognized as Safe) substance by the FDA. This does not indicate the ingredient is unsafe; rather, it reflects that formal GRAS status has not been petitioned or established through notice procedures. The ingredient may still be legally used in food under FDA food additive regulations or as part of traditional food manufacturing processes where it has a history of safe use.

The FDA maintains oversight of cottonseed-derived ingredients as part of its broader food safety authority. International regulatory bodies, including those in the European Union and other countries, have reviewed cottonseed ingredients and generally consider properly processed cottonseed products acceptable in food applications.

Key Studies

Scientific literature on cottonseed processing consistently demonstrates that heat treatment and oil extraction reduce antinutritional factors. Research on gossypol reduction through various processing methods shows that cooking and defating substantially lower this compound to levels considered safe for human consumption. Studies on the nutritional composition of processed cottonseed products indicate adequate protein quality and acceptable micronutrient profiles.

While extensive clinical trials specific to this exact ingredient formulation may be limited, the safety data derives from broader knowledge of cottonseed processing chemistry and historical food use patterns. Regulatory agencies rely on these established processing technologies and compositional data when evaluating cottonseed-derived ingredients.

Frequently Asked Questions

What is Cottonseed Flour, Partially Defatted, Cooked?

Cottonseed flour, partially defatted, cooked is a processed plant-derived ingredient made from cottonseed that has had most of its oil removed and been heat-treated. It functions as a processing aid in food manufacturing and is generally recognized as safe by food scientists, though it is not formally approved as GRAS by the FDA.

Is Cottonseed Flour, Partially Defatted, Cooked safe?

Cottonseed Flour, Partially Defatted, Cooked is currently rated "safe" based on FDA and EFSA data. It is approved in the US and not_evaluated in the EU. There are 0 FDA adverse event reports associated with this additive.

Is Cottonseed Flour, Partially Defatted, Cooked banned in any country?

Cottonseed Flour, Partially Defatted, Cooked is approved in the United States and not_evaluated in the European Union. Review the regulatory status cards above for the most current information.

Data Sources

Data is sourced exclusively from official government databases and updated periodically. This page does not constitute medical advice. Consult a healthcare professional for dietary guidance.