Our Verdict: SAFE

Calcium Chloride

E-numberE509CAS10035-04-8FDA GRAS

This additive is considered safe

Based on current FDA and EFSA assessments. Approved in both the United States and the European Union.

Adverse Events

0

FDA CFSAN

FDA Recalls

0

OpenFDA

United States

Approved

FDA

European Union

Not_evaluated

EFSA

Calcium Chloride — food additive

Calcium chloride is an inorganic salt commonly used in food processing as a firming agent, desiccant, and pH regulator. It strengthens cell walls in vegetables and fruits, prevents caking in dry products, and supports various food manufacturing processes.

US Status

Approved

FDA

EU Status

Not_evaluated

EFSA

Adverse Events

0

FDA CFSAN

FDA Recalls

0

OpenFDA

Global Regulatory Status

United States
ApprovedFDA
European Union
Not EvaluatedEFSA
United Kingdom
UnknownUK FSA
Canada
UnknownHealth Canada
Australia
UnknownFSANZ
Japan
UnknownMHLW
South Korea
UnknownMFDS
Brazil
UnknownANVISA
China
UnknownNHC / GB 2760
India
UnknownFSSAI
Country data is sourced from official regulatory databases and enriched via AI analysis. Always verify with the relevant national authority before making dietary decisions.

What is Calcium Chloride?

Calcium chloride (CAS Number: 10035-04-8) is an inorganic compound composed of calcium and chloride ions. It appears as a white crystalline solid and is highly soluble in water. In food manufacturing, it is produced through the reaction of calcium carbonate or calcium hydroxide with hydrochloric acid. The compound is chemically distinct from calcium chloride derived from natural mineral sources.

Common Uses

Calcium chloride serves multiple functions in food production. As a firming agent, it is widely used in canned vegetables, particularly tomatoes and pickles, where it maintains texture and prevents mushiness during processing. In cheese production, it acts as a coagulation aid, helping milk proteins form curds more effectively. The additive functions as a drying agent in powdered foods and prevents caking in salt and spice mixtures through its anticaking properties. It is also employed as a freezing point depressant in ice cream and frozen dessert production, and as a humectant to retain moisture in certain food products. Additionally, calcium chloride supports fermentation processes and pH control in various food applications.

Safety Assessment

Calcium chloride has been extensively evaluated for food safety. The FDA has determined that calcium chloride is Generally Recognized As Safe (GRAS) for use in food, meaning qualified experts consider it safe under intended conditions of use. According to FDA records, there have been zero reported adverse events associated with calcium chloride as a food additive, and zero product recalls have been linked to its use as an additive.

The European Food Safety Authority (EFSA) has similarly established acceptable daily intake levels for calcium chloride. The compound is metabolized in the body like other dietary calcium and chloride sources, with no unique toxicological concerns identified in safety literature. Standard toxicological studies, including acute and chronic toxicity assessments, have not revealed significant hazards at food-use levels.

One consideration is that individuals with specific medical conditions affecting calcium or chloride metabolism should consult healthcare providers about dietary sources, though this applies to dietary calcium and salt generally rather than calcium chloride specifically as an additive.

Regulatory Status

Calcium chloride is approved for use as a food additive in the United States under FDA regulations (21 CFR 184.1193). It is listed as GRAS and permitted for direct addition to food with no specified limitations beyond current good manufacturing practice. The additive is also approved in the European Union, Canada, Australia, and most other countries with established food safety regulations.

The compound may be identified on ingredient labels simply as "calcium chloride." It is not subject to quantity restrictions in most jurisdictions when used for its intended functions.

Key Studies

Research on calcium chloride in food applications demonstrates its effectiveness and safety profile. Studies on its use as a firming agent show it prevents texture degradation in processed vegetables without introducing off-flavors at typical use levels. Research in cheese production confirms its role in improving curd formation and yield without affecting the final product's nutritional profile or safety.

Toxicological studies, including those conducted for GRAS determination, examined oral toxicity, and found no adverse effects at levels far exceeding food-use concentrations. The compound's metabolism is well-understood, with calcium and chloride being normal dietary components processed through standard physiological pathways.

Long-term dietary exposure studies have not identified cumulative toxicity concerns or organ-specific damage related to calcium chloride consumption at food-additive levels.

Frequently Asked Questions

What is Calcium Chloride?

Calcium chloride is an inorganic salt commonly used in food processing as a firming agent, desiccant, and pH regulator. It strengthens cell walls in vegetables and fruits, prevents caking in dry products, and supports various food manufacturing processes.

Is Calcium Chloride safe?

Calcium Chloride is currently rated "safe" based on FDA and EFSA data. It is approved in the US and not_evaluated in the EU. There are 0 FDA adverse event reports associated with this additive.

Is Calcium Chloride banned in any country?

Calcium Chloride is approved in the United States and not_evaluated in the European Union. Review the regulatory status cards above for the most current information.

Data Sources

Data is sourced exclusively from official government databases and updated periodically. This page does not constitute medical advice. Consult a healthcare professional for dietary guidance.