# Vanillyl Butyl Ether

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**Safety rating:** UNKNOWN
**CAS number:** 82654-98-6
**Category:** flavoring
**FDA GRAS:** no
**Adverse events (FDA AERS):** 0
**FDA recalls:** 0
**Last updated:** 2026-04-04

## Summary

Vanillyl Butyl Ether (CAS 82654-98-6) is a synthetic flavoring agent designed to provide vanilla-like aromatic characteristics to food and beverage products. It functions as a flavoring adjuvant in the food industry but has not received FDA GRAS (Generally Recognized as Safe) status.

## Regulatory status

| Country | Status |
| --- | --- |
| United States | approved |
| European Union | not_evaluated |
| United Kingdom | approved |
| Canada | approved |
| Australia | approved |
| Japan | approved |
| South Korea | approved |
| Brazil | approved |
| China | approved |
| India | approved |

## Detailed analysis

## What is Vanillyl Butyl Ether?

Vanillyl Butyl Ether is a synthetic organic compound classified as a flavoring agent and flavoring adjuvant. It is a derivative compound structurally related to vanillin, the primary component responsible for vanilla's characteristic aroma and taste. With the CAS number 82654-98-6, this compound is manufactured through chemical synthesis rather than extracted from natural vanilla sources. The addition of a butyl ether group to the vanillyl structure creates a modified flavoring molecule with distinct sensory properties compared to natural or synthetic vanillin.

## Common Uses

Vanillyl Butyl Ether is employed in the food and beverage industry as a flavoring agent to impart vanilla-like or enhanced aromatic notes to various products. It functions as a flavoring adjuvant, meaning it may be used alongside other flavor compounds to achieve desired taste profiles. Potential applications include beverages, dairy products, baked goods, confectionery, and other processed foods where vanilla flavoring is desired. The compound allows manufacturers to create specific flavor characteristics that may differ subtly from traditional vanilla flavoring sources.

## Safety Assessment

As of the available data, there have been zero adverse events reported to the FDA associated with Vanillyl Butyl Ether, and no FDA recalls involving this substance have been documented. However, it is important to note that this additive has not received GRAS status from the FDA, meaning it has not undergone the formal FDA review process that results in official recognition as safe for its intended use. The absence of reported adverse events does not necessarily constitute formal safety approval; rather, it indicates no safety incidents have been documented in the FDA database. Limited published toxicological data is available for this specific compound in scientific literature, which is not uncommon for specialized synthetic flavoring agents used in relatively small quantities.

## Regulatory Status

Vanillyl Butyl Ether does not possess FDA GRAS designation, which distinguishes it from many common flavoring agents. GRAS status requires either substantial history of use before 1958 or approval following petition review by FDA or by a panel of qualified experts. The lack of GRAS status means manufacturers using this ingredient must comply with applicable FDA regulations for food additives, which may require adherence to specific limitations on use levels or specific food categories where it is permitted. The regulatory pathway and permitted uses for this ingredient may vary by jurisdiction and market. In the European Union, the regulatory framework for flavoring substances differs, and this compound's status under EFSA (European Food Safety Authority) assessment may differ from FDA determinations.

## Key Studies

Limited peer-reviewed literature is publicly available specifically addressing the safety profile of Vanillyl Butyl Ether as a distinct compound. Most safety evaluations of synthetic vanillin derivatives focus on structural categories and general toxicological principles for this class of compounds. Ether-based flavoring compounds have generally been evaluated for acute and chronic toxicity, with most demonstrating favorable safety profiles at typical use levels in food applications. The absence of reported safety concerns in FDA databases suggests no identified hazards have emerged from use, though the limited regulatory history and lack of formal safety petition approval indicate this ingredient may not be widely utilized in commercial food products. Manufacturers considering use of this flavoring agent should consult current FDA regulations and may need to seek regulatory guidance on appropriate usage levels and permitted food applications.

## Sources

- FDA Substances Added to Food (CFSAN)
- OpenFDA Adverse Event Reporting System (AERS)
- OpenFDA Food Recalls
- EFSA OpenFoodTox
- EU Food Additive Portal

## Citation

Additive Facts. "Vanillyl Butyl Ether — Safety, regulation, and evidence." https://additivefacts.com/additives/vanillyl-butyl-ether. Accessed 2026-05-20.