# Rhodinyl Butyrate

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**Safety rating:** SAFE
**CAS number:** 141-15-1
**Category:** flavoring
**FDA GRAS:** no
**Adverse events (FDA AERS):** 0
**FDA recalls:** 0
**Last updated:** 2026-04-04

## Summary

Rhodinyl butyrate (CAS 141-15-1) is a synthetic flavoring compound used to create rose-like and floral notes in food and beverage products. It functions as a flavoring agent or adjuvant in the food industry to enhance or modify taste and aroma profiles.

## Regulatory status

| Country | Status |
| --- | --- |
| United States | approved |
| European Union | not_evaluated |
| United Kingdom | approved |
| Canada | approved |
| Australia | approved |
| Japan | approved |
| South Korea | approved |
| Brazil | approved |
| China | approved |
| India | approved |

## Detailed analysis

## What is Rhodinyl Butyrate?

Rhodinyl butyrate is a synthetic organic compound classified as a flavoring agent. It is an ester composed of rhodinol (a naturally occurring alcohol found in rose oil and geranium oil) combined with butyric acid. The compound is identified by CAS Number 141-15-1 and is produced through chemical synthesis rather than extraction from natural sources.

## Common Uses

Rhodinyl butyrate is used primarily in the flavor industry to create or enhance floral notes in food and beverage products. Its rose-like aroma makes it valuable in confectionery, beverages, baked goods, and dairy products. The compound functions as part of complex flavor formulations where multiple aromatic compounds are combined to achieve desired taste and smell profiles. It is typically used in very small quantities, as is standard practice with synthetic flavoring agents.

## Safety Assessment

Rhodinyl butyrate has not been formally reviewed or approved by the FDA under its Generally Recognized as Safe (GRAS) process. However, the absence of FDA GRAS status does not necessarily indicate safety concerns. The compound has generated zero reported adverse events according to FDA surveillance data and has been associated with zero product recalls. This lack of negative safety reports suggests no known toxicity issues have emerged from its use in food applications.

The flavoring industry maintains rigorous safety standards for synthetic flavor compounds. Flavoring agents are typically used at very low concentrations—often in parts per million—which significantly reduces potential exposure risks. The safety profile of flavoring compounds is generally established through toxicological testing, including acute toxicity studies, and assessment of potential genotoxicity and reproductive effects.

## Regulatory Status

While not FDA GRAS-approved in the United States, rhodinyl butyrate is used as a flavoring ingredient in food products. In the European Union, flavoring substances are regulated under Regulation (EC) No 1334/2008, which establishes specific safety criteria for flavor compounds used in food. Many synthetic flavoring agents used in the U.S. are evaluated and approved by the Flavor and Extract Manufacturers' Association (FEMA) under their Expert Panel process, which assesses safety based on current scientific data.

The lack of FDA GRAS status may reflect that manufacturers have not pursued formal GRAS notification, rather than an indication that the substance is unsafe. Many flavoring compounds operate under the existing regulatory framework for food additives without requiring explicit GRAS status.

## Key Studies

Limited published peer-reviewed research specifically addresses rhodinyl butyrate. However, the compound's chemical composition—as an ester derived from naturally occurring materials—suggests a relatively low toxicity profile. Related flavor compounds and their metabolic pathways have been studied more extensively. Butyric acid esters in general are recognized as safe ingredients in food applications, and rhodinol-based compounds have historical use in the fragrance industry.

Flavor safety assessments typically rely on structural similarity to known safe compounds, quantitative risk assessment based on intended use levels, and toxicological data from animal and cell-based studies. The lack of adverse events and recalls associated with this compound suggests it has not raised safety concerns in practical food use.

## Sources

- FDA Substances Added to Food (CFSAN)
- OpenFDA Adverse Event Reporting System (AERS)
- OpenFDA Food Recalls
- EFSA OpenFoodTox
- EU Food Additive Portal

## Citation

Additive Facts. "Rhodinyl Butyrate — Safety, regulation, and evidence." https://additivefacts.com/additives/rhodinyl-butyrate. Accessed 2026-05-20.
