# Protein, Animal, Hydrolyzed

> Source URL: https://additivefacts.com/additives/protein-animal-hydrolyzed
> Markdown URL: https://additivefacts.com/additives/protein-animal-hydrolyzed.md

**Safety rating:** SAFE
**CAS number:** 100085-61-8
**Category:** flavoring
**FDA GRAS:** no
**Adverse events (FDA AERS):** 0
**FDA recalls:** 0
**Last updated:** 2026-04-04

## Summary

Hydrolyzed Animal Protein is a flavor enhancer derived from the breakdown of animal-based proteins through chemical or enzymatic processes. It is used in food products to intensify and improve flavor profiles, functioning similarly to other umami-enhancing ingredients.

## Regulatory status

| Country | Status |
| --- | --- |
| United States | approved |
| European Union | not_evaluated |
| United Kingdom | approved |
| Canada | approved |
| Australia | approved |
| Japan | approved |
| South Korea | approved |
| Brazil | approved |
| China | approved |
| India | approved |

## Detailed analysis

## What is Hydrolyzed Animal Protein?

Hydrolyzed Animal Protein (HAP) is a food ingredient produced by breaking down animal proteins—typically from sources such as meat, poultry, fish, or dairy—through hydrolysis. This process involves using acids, bases, or enzymes to break peptide bonds, resulting in a mixture of amino acids, peptides, and other nitrogen-containing compounds. The hydrolysis process concentrates flavor compounds naturally present in the protein source, creating an ingredient that enhances the taste profile of foods.

## Common Uses

Hydrolyzed Animal Protein is primarily used as a flavoring agent and flavor enhancer in processed foods. Common applications include:

- Meat broths and bouillons
- Soups and soup mixes
- Gravies and sauces
- Savory snacks and seasonings
- Pet food formulations
- Ready-to-eat meals

The ingredient functions by providing umami taste—the savory, mouth-filling sensation associated with glutamates and nucleotides—thereby reducing the need for added salt or artificial flavors in formulations.

## Safety Assessment

Hydrolyzed Animal Protein has not been formally affirmed as Generally Recognized As Safe (GRAS) by the FDA, meaning it does not have the agency's explicit safety determination. However, this designation does not indicate the ingredient is unsafe; rather, it reflects that formal FDA review under the GRAS process has not occurred or been completed.

Importantly, the FDA has received zero adverse event reports associated with this ingredient and zero recalls have been issued. This absence of documented harm in the U.S. market suggests the ingredient has not caused recognizable safety concerns in consumer populations.

Historically, hydrolyzed proteins have been used in food production for decades without widespread safety incidents. The ingredient is generally recognized as a source of amino acids, which are nutritionally beneficial compounds. However, some hydrolyzed protein products may contain elevated sodium levels depending on the production process, which is relevant for consumers monitoring sodium intake.

Certain individuals with specific protein sensitivities or allergies should verify the animal source of hydrolysis, as the ingredient may retain allergenic properties of its source material.

## Regulatory Status

In the United States, Hydrolyzed Animal Protein is permitted for use as a flavoring agent under FDA regulations, though it operates without formal GRAS affirmation. This means manufacturers can use it based on the general regulatory framework allowing food additives, but without the additional assurance of an FDA GRAS determination.

The ingredient is subject to FDA compliance with current Good Manufacturing Practices (cGMP) and must meet labeling requirements that identify it appropriately on ingredient lists. In the European Union, hydrolyzed proteins derived from animal sources face more stringent regulations and specific categorization requirements.

## Key Studies

Limited peer-reviewed research specifically isolates and studies Hydrolyzed Animal Protein as a discrete ingredient. Most scientific literature addresses hydrolyzed proteins broadly, focusing on nutritional composition and amino acid bioavailability rather than safety toxicology.

General research on hydrolyzed proteins demonstrates:

- Amino acid profiles vary depending on source material and hydrolysis method
- Proteins are broken into smaller units more readily absorbed than intact proteins
- No systematic toxicological studies have identified inherent hazards from the hydrolysis process itself
- Contaminant profiles depend on source material quality and processing standards

The absence of formal safety studies through controlled toxicological assessment represents a data gap, though the long history of use in food production without documented harm provides indirect safety support.

## Conclusion

Hydrolyzed Animal Protein remains an understudied but apparently safe ingredient based on historical use patterns and the complete absence of adverse event reports. The lack of FDA GRAS affirmation reflects incomplete formal review rather than identified safety concerns.

## Sources

- FDA Substances Added to Food (CFSAN)
- OpenFDA Adverse Event Reporting System (AERS)
- OpenFDA Food Recalls
- EFSA OpenFoodTox
- EU Food Additive Portal

## Citation

Additive Facts. "Protein, Animal, Hydrolyzed — Safety, regulation, and evidence." https://additivefacts.com/additives/protein-animal-hydrolyzed. Accessed 2026-05-20.