# Poly(divinylbenzene-co-trimethyl(vinylbenzyl)ammonium Chloride)

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**Safety rating:** UNKNOWN
**CAS number:** 60177-39-1
**Category:** other
**FDA GRAS:** no
**Adverse events (FDA AERS):** 0
**FDA recalls:** 0
**Last updated:** 2026-04-04

## Summary

Poly(divinylbenzene-co-trimethyl(vinylbenzyl)ammonium chloride) is a synthetic polymer used as a processing aid in food manufacturing. It functions to remove or modify unwanted substances during production, with no approved food uses in major regulatory regions.

## Regulatory status

| Country | Status |
| --- | --- |
| United States | approved |
| European Union | not_evaluated |
| United Kingdom | approved |
| Canada | approved |
| Australia | approved |
| Japan | approved |
| South Korea | approved |
| Brazil | approved |
| China | approved |
| India | approved |

## Detailed analysis

## What is Poly(divinylbenzene-co-trimethyl(vinylbenzyl)ammonium Chloride)?

Poly(divinylbenzene-co-trimethyl(vinylbenzyl)ammonium chloride), identified by CAS number 60177-39-1, is a synthetic ion-exchange polymer composed of cross-linked divinylbenzene with quaternary ammonium functional groups. This copolymer belongs to a class of water-treatment and purification polymers commonly used in industrial applications. The polymer's structure allows it to selectively bind and remove certain molecules from liquid solutions, making it useful in various manufacturing processes.

## Common Uses

As a processing aid, this polymer is utilized in food manufacturing to remove or reduce levels of specific compounds during production. Processing aids are ingredients used to perform a technological function during the manufacturing process but are typically removed or reduced to insignificant levels before the food is consumed. Common applications for similar ion-exchange polymers include clarification of juices, removal of color compounds, decolorization of syrups, and purification of food ingredients. However, specific approved uses for this particular polymer in food manufacturing are limited in major regulatory jurisdictions.

## Safety Assessment

According to FDA data, there have been zero reported adverse events associated with this additive and zero product recalls involving it. This absence of adverse event reports suggests minimal consumer safety concerns, though it should be noted that the lack of reported incidents does not necessarily indicate extensive human exposure or consumption.

The polymer's chemical structure—a cross-linked polymer with quaternary ammonium groups—is generally considered to have low systemic bioavailability due to its large molecular weight and polymeric nature, meaning it is unlikely to be absorbed into the bloodstream in significant amounts if ingested. Most concern with such polymers centers on potential leaching of unreacted monomers or oligomers, which would depend on manufacturing quality and residual monomer levels.

No significant adverse health effects have been documented in available scientific literature for this specific polymer. Toxicological concerns typically focus on the purity of the polymer preparation and the levels of unreacted starting materials or degradation products.

## Regulatory Status

This additive is not approved as a food additive under FDA regulations and does not have GRAS (Generally Recognized As Safe) status in the United States. GRAS status requires either a history of safe use prior to 1958 or completion of extensive toxicological and safety testing submitted to the FDA. Without GRAS status or specific FDA approval, this polymer cannot be intentionally added to foods sold in the US market.

Regulatory status varies internationally. The European Food Safety Authority (EFSA) evaluates food additives differently, and approval status in the EU may differ from US regulations. Manufacturers seeking to use processing aids must verify compliance with regulations in each country where products are marketed.

## Key Studies

Limited published research specifically addresses this polymer's use in food applications. Most scientific literature on similar quaternary ammonium polymers focuses on their efficacy as water treatment materials and ion-exchange resins in industrial settings. Studies on related polymers have generally demonstrated low toxicity and minimal absorption when ingested, though specific toxicological studies on this particular polymer appear limited in published scientific databases.

Further research and regulatory guidance would be needed to establish safety parameters for food use. Manufacturers or researchers interested in pursuing food applications would need to conduct comprehensive toxicological studies, including acute and chronic toxicity assessments, to support potential regulatory submissions.

## Sources

- FDA Substances Added to Food (CFSAN)
- OpenFDA Adverse Event Reporting System (AERS)
- OpenFDA Food Recalls
- EFSA OpenFoodTox
- EU Food Additive Portal

## Citation

Additive Facts. "Poly(divinylbenzene-co-trimethyl(vinylbenzyl)ammonium Chloride) — Safety, regulation, and evidence." https://additivefacts.com/additives/poly-divinylbenzene-co-trimethyl-vinylbenzyl-ammonium-chloride. Accessed 2026-05-20.