# Menthadienol

> Source URL: https://additivefacts.com/additives/menthadienol
> Markdown URL: https://additivefacts.com/additives/menthadienol.md

**Safety rating:** UNKNOWN
**CAS number:** 3269-90-7
**Category:** flavoring
**FDA GRAS:** no
**Adverse events (FDA AERS):** 0
**FDA recalls:** 0
**Last updated:** 2026-04-02

## Summary

Menthadienol is a naturally-derived flavoring compound classified as a masticatory substance used to impart mint and cooling sensations in food and beverage products. It functions as both a flavoring agent and flavor adjuvant in processed foods.

## Regulatory status

| Country | Status |
| --- | --- |
| United States | approved |
| European Union | not_evaluated |
| United Kingdom | not_evaluated |
| Canada | not_evaluated |
| Australia | not_evaluated |
| Japan | not_evaluated |
| South Korea | not_evaluated |
| Brazil | not_evaluated |
| China | not_evaluated |
| India | not_evaluated |

## Detailed analysis

## What is Menthadienol?

Menthadienol (CAS Number 3269-90-7) is an organic compound belonging to the class of terpene-derived flavoring agents. It is structurally related to menthol and other mint-derived compounds. The substance exists as a colorless to pale yellow liquid with characteristic minty and cooling organoleptic properties. Menthadienol is classified as a flavoring agent and masticatory substance, meaning it can be used both to impart flavor and as a component in chewing gum and similar products.

## Common Uses

Menthadienol is employed in the food industry primarily as a flavoring ingredient in:

- Chewing gums and masticatory products
- Mint-flavored candies and lozenges
- Beverages including alcoholic and non-alcoholic drinks
- Confectionery products
- Oral care products such as toothpaste and mouthwash
- Pharmaceutical preparations requiring mint flavoring

The cooling and numbing sensation it provides makes it valuable in products where a refreshing minty note is desired. It is often used in combination with other mint-derived compounds to achieve desired flavor profiles.

## Safety Assessment

According to FDA records, menthadienol has generated zero reported adverse events and zero product recalls. The absence of adverse event reports in the FDA database suggests no significant safety concerns have been formally documented in the United States food supply. However, it is important to note that the lack of reported adverse events does not constitute formal FDA approval or GRAS (Generally Recognized as Safe) status—menthadienol is not currently on the FDA's GRAS list.

As a terpene-derived compound structurally similar to naturally occurring mint constituents, menthadienol shares chemical characteristics with substances that have been used historically in foods and beverages. The typical use levels in food products are relatively low, which may contribute to the absence of safety concerns in available data.

For individuals with known sensitivities to mint-derived compounds or menthol-containing products, menthadienol-containing foods should be consumed with awareness of personal tolerances. Limited data exists on high-dose exposure or long-term consumption patterns.

## Regulatory Status

Menthadienol does not hold FDA GRAS status, meaning it has not been formally affirmed as generally recognized as safe by the FDA through either the GRAS Notice Program or formal rulemaking. Despite this, it is permitted for use in food products in certain jurisdictions under flavor and fragrance regulations.

In the European Union, menthadienol may be used as a flavoring substance subject to EFSA (European Food Safety Authority) guidelines and regulations under Regulation (EC) No. 1334/2008. Its use is subject to maximum permitted levels and specifications established by regulatory authorities.

Manufacturers using menthadienol in food products must ensure compliance with applicable regulations in their target markets, as regulatory status varies by country and region.

## Key Studies

Scientific literature on menthadienol specifically is limited, with most research focusing on related compounds such as menthol and other mint-derived terpenes. General toxicology studies on structurally similar mint compounds indicate low systemic toxicity at typical food-use levels. The terpene class of compounds has been extensively studied, with most members demonstrating favorable safety profiles when used at appropriate concentrations in food and beverage applications.

Additional research specifically examining menthadienol's safety profile, absorption, metabolism, and potential interactions would contribute to a more comprehensive understanding of this flavoring agent. Current safety assessments rely largely on structural similarity to approved mint compounds and absence of reported adverse events.

## Sources

- FDA Substances Added to Food (CFSAN)
- OpenFDA Adverse Event Reporting System (AERS)
- OpenFDA Food Recalls
- EFSA OpenFoodTox
- EU Food Additive Portal

## Citation

Additive Facts. "Menthadienol — Safety, regulation, and evidence." https://additivefacts.com/additives/menthadienol. Accessed 2026-05-19.