# Heptyl Formate

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> Markdown URL: https://additivefacts.com/additives/heptyl-formate.md

**Safety rating:** UNKNOWN
**CAS number:** 112-23-2
**Category:** flavoring
**FDA GRAS:** no
**Adverse events (FDA AERS):** 0
**FDA recalls:** 0
**Last updated:** 2026-04-02

## Summary

Heptyl formate (CAS 112-23-2) is an organic ester compound used as a flavoring agent in food products. It is not currently approved as a Generally Recognized as Safe (GRAS) substance by the FDA, though it has no reported adverse events or recalls associated with its use.

## Regulatory status

| Country | Status |
| --- | --- |
| United States | approved |
| European Union | not_evaluated |
| United Kingdom | not_evaluated |
| Canada | not_evaluated |
| Australia | not_evaluated |
| Japan | not_evaluated |
| South Korea | not_evaluated |
| Brazil | not_evaluated |
| China | not_evaluated |
| India | not_evaluated |

## Detailed analysis

## What is Heptyl Formate?

Heptyl formate is an organic ester formed from the combination of formic acid and heptanol. It is a colorless to pale yellow liquid with a fruity, apple-like odor. The compound has a molecular formula of C₈H₁₆O₂ and is identified by CAS number 112-23-2. As a naturally occurring volatile compound found in small quantities in various fruits, heptyl formate functions as a flavoring agent that contributes to the aroma and taste profiles of foods.

## Common Uses

Heptyl formate is employed in the food industry as a synthetic flavoring agent to enhance or replicate fruity, particularly apple-like, flavors in beverages, confectionery, baked goods, and other processed foods. Its fruity organoleptic properties make it useful in formulating flavor compounds for both beverages and dry food products. The compound is utilized at very low concentrations, typically measured in parts per million (ppm), which is standard practice for most volatile flavoring agents in food manufacturing.

## Safety Assessment

According to FDA records, there are zero reported adverse events associated with heptyl formate, and no product recalls have been issued involving this additive. The absence of adverse event reports and recalls provides an initial indication of safety in practical food applications. However, it is important to note that heptyl formate has not been formally evaluated and approved as a GRAS substance by the FDA, which means it does not have explicit regulatory recognition in the United States for use as a food additive.

The compound's safety profile is further supported by its structural similarity to other approved formate esters and the fact that it exists naturally in fruits at trace levels. Toxicological data on heptyl formate, while limited in the public literature, would typically focus on acute and subchronic toxicity assessments, which are standard requirements for flavor ingredient approval in major regulatory jurisdictions.

## Regulatory Status

In the United States, heptyl formate does not carry GRAS (Generally Recognized as Safe) status from the FDA. This means manufacturers cannot use this additive without formal FDA approval under a food additive petition or other regulatory pathway. However, some countries may permit its use under different regulatory frameworks. The European Food Safety Authority (EFSA) and other international regulatory bodies may have different assessments and approval statuses for this ingredient.

Manufacturers seeking to use heptyl formate in food products would need to consult current regulations in their specific market and may need to obtain formal approval before commercialization. Regulatory requirements vary significantly between jurisdictions, and what is permitted in one country may be restricted or prohibited in another.

## Key Studies

Published scientific literature specifically focused on heptyl formate as a food additive is limited. Most information about the safety of flavor esters derives from broader toxicological studies on formate esters and ester compounds generally. Standard safety assessments for flavor ingredients typically include acute oral toxicity studies, irritation and sensitization testing, and evaluation of metabolic pathways. These studies help establish safe levels of use (Acceptable Daily Intake or ADI) for food additives. Additional research and formal safety evaluations may be necessary to support regulatory approval in major markets like the United States and European Union.

## Sources

- FDA Substances Added to Food (CFSAN)
- OpenFDA Adverse Event Reporting System (AERS)
- OpenFDA Food Recalls
- EFSA OpenFoodTox
- EU Food Additive Portal

## Citation

Additive Facts. "Heptyl Formate — Safety, regulation, and evidence." https://additivefacts.com/additives/heptyl-formate. Accessed 2026-05-19.