# Glucosidase From Aspergillus Flavus

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**Safety rating:** UNKNOWN
**CAS number:** 977091-48-7
**Category:** other
**FDA GRAS:** no
**Adverse events (FDA AERS):** 0
**FDA recalls:** 0
**Last updated:** 2026-04-02

## Summary

Glucosidase from Aspergillus flavus is an enzyme used in food processing to break down glucosides into simpler sugars and other compounds. It functions as a processing aid in various food manufacturing applications where enzymatic hydrolysis is desired.

## Regulatory status

| Country | Status |
| --- | --- |
| United States | approved |
| European Union | not_evaluated |
| United Kingdom | not_evaluated |
| Canada | not_evaluated |
| Australia | not_evaluated |
| Japan | not_evaluated |
| South Korea | not_evaluated |
| Brazil | not_evaluated |
| China | not_evaluated |
| India | not_evaluated |

## Detailed analysis

## What is Glucosidase From Aspergillus Flavus?

Glucosidase from Aspergillus flavus is an enzyme derived from the fungus Aspergillus flavus. Enzymes are proteins that catalyze specific biochemical reactions. This particular glucosidase catalyzes the hydrolysis of glycosidic bonds in glucosides, converting them into glucose and aglycones (non-sugar components). The enzyme is classified as a processing aid in food manufacturing, where it facilitates the breakdown of complex carbohydrates and glucoside compounds during food production.

## Common Uses

Glucosidase from Aspergillus flavus is employed in food processing applications where enzymatic breakdown of glucosides is beneficial. Potential applications include beverage production, particularly in juice and wine processing, where it may enhance flavor development and clarity. The enzyme may also be used in other food manufacturing processes requiring glucoside hydrolysis. As a processing aid, the enzyme itself is typically inactivated or removed during processing, meaning residual enzyme levels in the final food product are generally minimal or undetectable.

## Safety Assessment

The safety profile of glucosidase from Aspergillus flavus is characterized by limited but notable data. According to FDA records, there have been zero reported adverse events associated with this enzyme, and no product recalls involving this ingredient have been documented. However, the enzyme does not currently hold GRAS (Generally Recognized as Safe) status with the FDA, which indicates that formal safety evaluation through the FDA's GRAS notification process has not been completed or accepted.

General safety considerations for enzymes from Aspergillus species include potential allergenicity and the importance of source strain documentation. Aspergillus flavus strains used for enzyme production should be verified to be non-toxigenic, as some wild-type strains of this species can produce aflatoxins, which are toxic secondary metabolites. Modern enzyme production typically employs controlled, documented strains with confirmed non-toxigenic characteristics. The enzyme's protein nature means it is susceptible to denaturation during food processing, particularly through heating, which reduces potential biological activity in final products.

## Regulatory Status

Glucosidase from Aspergillus flavus does not have FDA GRAS status. This means it has not been formally affirmed or notified to the FDA as generally recognized as safe through either premarket approval or the GRAS notification process. Companies using this enzyme in food products must ensure compliance with applicable FDA regulations for food additives and processing aids. Regulatory status may vary by country; approval in one jurisdiction does not guarantee approval in another. Manufacturers should verify current regulatory requirements in their specific markets before use.

## Key Studies

Published scientific literature on glucosidase from Aspergillus flavus in food applications is limited. General enzyme safety assessment principles, as established by regulatory bodies including the FDA and EFSA (European Food Safety Authority), evaluate enzyme preparations based on source organism characteristics, production methods, enzymatic specificity, potential for residual enzyme in food products, and allergenicity. The absence of reported adverse events and recalls suggests no acute safety signals have emerged from current use, though this does not constitute comprehensive safety approval. Additional toxicological or allergenicity studies specific to this enzyme preparation may be warranted to support GRAS determination or regulatory approval in various jurisdictions.

## Sources

- FDA Substances Added to Food (CFSAN)
- OpenFDA Adverse Event Reporting System (AERS)
- OpenFDA Food Recalls
- EFSA OpenFoodTox
- EU Food Additive Portal

## Citation

Additive Facts. "Glucosidase From Aspergillus Flavus — Safety, regulation, and evidence." https://additivefacts.com/additives/glucosidase-from-aspergillus-flavus. Accessed 2026-05-19.