# Anisic Acid

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**Safety rating:** UNKNOWN
**CAS number:** 1335-08-6
**Category:** flavoring
**FDA GRAS:** no
**Adverse events (FDA AERS):** 0
**FDA recalls:** 0
**Last updated:** 2026-04-02

## Summary

Anisic acid is an organic compound derived from anise with a characteristic aromatic scent. It is used in the food industry as a flavoring agent and flavor enhancer to impart anise-like notes to beverages, confections, and other food products.

## Regulatory status

| Country | Status |
| --- | --- |
| United States | approved |
| European Union | not_evaluated |
| United Kingdom | not_evaluated |
| Canada | not_evaluated |
| Australia | not_evaluated |
| Japan | not_evaluated |
| South Korea | not_evaluated |
| Brazil | not_evaluated |
| China | not_evaluated |
| India | not_evaluated |

## Detailed analysis

## What is Anisic Acid?

Anisic acid (CAS Number: 1335-08-6) is an organic carboxylic acid with a molecular formula of C8H8O3. It is a naturally occurring compound found in anise seeds and other plants, characterized by a distinct aromatic odor reminiscent of anise. The compound exists in multiple isomeric forms, with p-anisic acid being the most commercially relevant. Anisic acid belongs to the methoxybenzene family of compounds and is chemically related to benzoic acid, a more widely used food additive.

## Common Uses

Anisic acid functions primarily as a flavoring agent and flavor enhancer in the food and beverage industry. It is used to create or enhance anise and licorice notes in a variety of food products, including:

- Alcoholic beverages and liqueurs
- Confectionery products
- Baked goods
- Flavored beverages and soft drinks
- Seasoning blends

The compound's aromatic properties make it valuable for formulators seeking to achieve specific flavor profiles without relying solely on essential oils or natural anise extracts. Its use is typically at very low concentrations, measured in parts per million, where its flavoring impact is most effective.

## Safety Assessment

Anisic acid has not been designated as Generally Recognized As Safe (GRAS) by the FDA, meaning it does not have blanket approval for use in food. However, the available safety data does not indicate significant concerns. The FDA has recorded zero adverse events associated with anisic acid and zero product recalls involving this ingredient.

From a toxicological perspective, anisic acid is considered to have low acute toxicity. Animal studies have not revealed significant organ toxicity at reasonable exposure levels. The compound is metabolized relatively quickly in the body and does not appear to accumulate in tissues. As with all food additives, safety depends heavily on the levels of exposure—anisic acid is used only at trace concentrations in food applications.

Individuals with sensitivities to anise or related compounds should exercise caution, though such sensitivities are relatively uncommon. The aromatic nature of the compound means that off-flavors or unintended sensory effects could occur at higher-than-intended concentrations.

## Regulatory Status

Anisic acid's regulatory status varies by jurisdiction. While not FDA GRAS-listed in the United States, it may be used in food under specific regulatory frameworks depending on the product category and intended use. In the European Union, anisic acid may be permitted as a flavoring substance under the EU's flavoring regulations, though approval depends on demonstrating safety at proposed use levels.

The lack of GRAS status in the U.S. does not necessarily indicate safety concerns; rather, it reflects that a formal GRAS petition has not been submitted or approved through FDA channels. Food manufacturers wishing to use anisic acid in the United States should verify compliance with applicable regulations and may need to submit safety data if marketing new products containing this ingredient.

## Key Studies

Limited published research specifically addresses anisic acid in isolation, as much of the safety data derives from broader studies on anise-derived compounds and related benzoic acid derivatives. Available toxicological data suggest anisic acid has an acceptable margin of safety when used at typical flavoring concentrations.

Studies on structurally similar compounds like benzoic acid and p-methoxybenzene derivatives provide relevant safety context. These investigations have generally supported the use of such compounds at trace levels in food applications. However, additional specific safety data on anisic acid would strengthen the evidence base for broader regulatory approval.

The absence of adverse event reports and recalls in FDA databases suggests that any anisic acid currently used in food products has not caused documented safety issues in the U.S. market.

## Sources

- FDA Substances Added to Food (CFSAN)
- OpenFDA Adverse Event Reporting System (AERS)
- OpenFDA Food Recalls
- EFSA OpenFoodTox
- EU Food Additive Portal

## Citation

Additive Facts. "Anisic Acid — Safety, regulation, and evidence." https://additivefacts.com/additives/anisic-acid. Accessed 2026-05-19.