# (+/-)-3-mercapto-1-butyl Acetate

> Source URL: https://additivefacts.com/additives/3-mercapto-1-butyl-acetate
> Markdown URL: https://additivefacts.com/additives/3-mercapto-1-butyl-acetate.md

**Safety rating:** UNKNOWN
**CAS number:** 89534-38-3
**Category:** flavoring
**FDA GRAS:** no
**Adverse events (FDA AERS):** 0
**FDA recalls:** 0
**Last updated:** 2026-04-02

## Summary

(+/-)-3-mercapto-1-butyl Acetate is a synthetic flavoring compound containing a sulfur-based chemical structure that imparts savory, meaty, and sulfurous aromatic notes to food products. It is used in small quantities as a flavoring agent in processed foods to enhance taste complexity.

## Regulatory status

| Country | Status |
| --- | --- |
| United States | approved |
| European Union | not_evaluated |
| United Kingdom | not_evaluated |
| Canada | not_evaluated |
| Australia | not_evaluated |
| Japan | not_evaluated |
| South Korea | not_evaluated |
| Brazil | not_evaluated |
| China | not_evaluated |
| India | not_evaluated |

## Detailed analysis

## What is (+/-)-3-mercapto-1-butyl Acetate?

(+/-)-3-mercapto-1-butyl Acetate (CAS Number: 89534-38-3) is a synthetic organic compound belonging to the class of sulfur-containing flavor compounds. The molecule contains a thiol group (mercapto, -SH), which is responsible for its characteristic pungent, savory character. The acetate ester component modulates volatility and flavor release during consumption. This compound exists as a racemic mixture, meaning it contains equal amounts of both left-handed and right-handed molecular configurations.

## Common Uses

This flavoring agent is primarily used in the food industry to provide savory, meaty, and umami-like flavor notes. Common applications include:

- Processed meat products and meat flavor systems
- Savory snack seasonings
- Soup and broth flavorings
- Processed cheese products
- Savory sauce and condiment bases

The compound is typically used in very small concentrations (parts per million range) due to its potent flavor impact. Its sulfur-based chemistry allows food manufacturers to achieve complex, realistic meat and savory flavor profiles without using large quantities of animal-derived ingredients.

## Safety Assessment

The FDA has not granted this compound Generally Recognized As Safe (GRAS) status, which means it operates under FDA regulations for food additives but requires pre-market approval before use. However, the absence of GRAS status does not indicate safety concerns—rather, it reflects that the regulatory pathway used may be different or that comprehensive safety dossiers have not been formally submitted for GRAS affirmation.

According to FDA records, there have been zero reported adverse events associated with this additive and zero recalls attributed to it, indicating no documented safety incidents in the U.S. food supply. The lack of adverse event reports suggests either minimal widespread use, excellent safety margins, or both.

As a synthetic flavoring compound, exposure levels are typically very low due to its potent flavor characteristics and the minimal quantities required for effect. Thiol-containing compounds are naturally present in foods like garlic and cruciferous vegetables, though this synthetic version is produced through chemical synthesis rather than extraction.

## Regulatory Status

In the United States, this additive's regulatory status depends on the food product category and whether it has undergone FDA approval as a food additive. It is not listed as a GRAS substance, meaning any manufacturer using it would need either FDA approval or reliance on a prior sanctioned status.

The European Food Safety Authority (EFSA) maintains separate approval lists for flavoring agents. International regulatory approaches vary, with some countries adopting more permissive frameworks for synthetic flavorings while others require specific approvals.

Manufacturers using this compound must maintain compliance with labeling regulations, ingredient disclosure requirements, and quantity limitations established by relevant regulatory agencies. Food products containing this ingredient must list it appropriately on product labels as a "flavoring" or similar descriptor.

## Key Studies

Limited published scientific literature specifically addresses this individual compound's safety profile. Sulfur-containing flavor compounds as a chemical class have been studied for their sensory properties and volatile profiles, with research demonstrating their effectiveness in creating savory flavor characteristics at extremely low concentrations.

Safety assessments of similar thiol-ester flavor compounds have generally shown low oral toxicity in animal models, consistent with their minimal use levels and chemical properties. The absence of regulatory alerts or safety warnings from major food safety organizations suggests acceptable risk profiles within established use parameters.

## Sources

- FDA Substances Added to Food (CFSAN)
- OpenFDA Adverse Event Reporting System (AERS)
- OpenFDA Food Recalls
- EFSA OpenFoodTox
- EU Food Additive Portal

## Citation

Additive Facts. "(+/-)-3-mercapto-1-butyl Acetate — Safety, regulation, and evidence." https://additivefacts.com/additives/3-mercapto-1-butyl-acetate. Accessed 2026-05-19.