# 1,5-octadien-3-one

> Source URL: https://additivefacts.com/additives/1-5-octadien-3-one
> Markdown URL: https://additivefacts.com/additives/1-5-octadien-3-one.md

**Safety rating:** UNKNOWN
**CAS number:** 65213-86-7
**Category:** flavoring
**FDA GRAS:** no
**Adverse events (FDA AERS):** 0
**FDA recalls:** 0
**Last updated:** 2026-04-02

## Summary

1,5-octadien-3-one (CAS 65213-86-7) is an organic compound used as a flavoring agent in food products. It is not currently approved as a Generally Recognized As Safe (GRAS) substance by the FDA but has no documented adverse events or recalls.

## Regulatory status

| Country | Status |
| --- | --- |
| United States | approved |
| European Union | not_evaluated |
| United Kingdom | not_evaluated |
| Canada | not_evaluated |
| Australia | not_evaluated |
| Japan | not_evaluated |
| South Korea | not_evaluated |
| Brazil | not_evaluated |
| China | not_evaluated |
| India | not_evaluated |

## Detailed analysis

## What is 1,5-octadien-3-one?

1,5-octadien-3-one is a naturally occurring organic compound classified as a ketone with two double bonds (a dienone structure). The compound is identified by CAS Number 65213-86-7 and belongs to the family of volatile flavor compounds found in various botanical sources. Its chemical structure contributes distinct aromatic and flavor properties that make it useful in food flavoring applications.

## Common Uses

1,5-octadien-3-one is employed as a flavoring agent and flavor adjuvant in the food industry. Flavoring agents in this chemical class are typically used in small quantities to impart or enhance specific taste and aroma characteristics in processed foods, beverages, and food preparations. The compound's volatile nature makes it suitable for applications where aromatic compounds are desired, though specific food product categories utilizing this ingredient are limited in publicly available information.

## Safety Assessment

According to FDA records, there are no reported adverse events or food recalls associated with 1,5-octadien-3-one. This absence of documented safety incidents suggests the compound has not raised significant health concerns in regulatory monitoring systems. However, the lack of adverse events does not constitute formal safety approval, as the substance has not undergone the comprehensive GRAS (Generally Recognized As Safe) review process by the FDA.

The compound's safety profile remains largely based on limited toxicological data in the public domain. Flavoring agents are generally used at very low concentrations in food products, which is an important consideration when evaluating potential exposure. The volatile nature of the compound may also limit systemic absorption following ingestion.

## Regulatory Status

1,5-octadien-3-one does not currently hold GRAS status from the FDA, meaning it has not been formally recognized as safe for its intended use in food. Despite this, the absence of regulatory restrictions or bans indicates the substance is not prohibited in food applications. In the European Union, the regulatory approach to flavoring compounds differs, with EFSA (European Food Safety Authority) maintaining separate evaluations for approved flavoring substances.

The lack of GRAS status suggests this ingredient may be used under specific regulatory provisions or may have limited commercial application in the United States food supply. Manufacturers using such compounds typically must ensure compliance with applicable food safety regulations and may need to provide safety documentation to regulatory authorities.

## Key Studies

Publicly available toxicological studies specifically examining 1,5-octadien-3-one are limited. Most safety information regarding similar flavoring compounds in this chemical class comes from broader evaluations of volatile organic compounds used in food flavoring. The compound's structural similarity to other approved flavor compounds provides some basis for hazard assessment, though direct empirical data specific to this substance would strengthen the evidence base.

Regulatory agencies typically evaluate flavoring compounds based on chemical structure, intended use levels, metabolic pathways, and any available toxicological data. For compounds without extensive published research, the burden of proof for safety documentation typically rests with manufacturers seeking regulatory approval or market authorization.

## Sources

- FDA Substances Added to Food (CFSAN)
- OpenFDA Adverse Event Reporting System (AERS)
- OpenFDA Food Recalls
- EFSA OpenFoodTox
- EU Food Additive Portal

## Citation

Additive Facts. "1,5-octadien-3-one — Safety, regulation, and evidence." https://additivefacts.com/additives/1-5-octadien-3-one. Accessed 2026-05-19.