# 1-(2-furyl)-1,3-butanedione

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**Safety rating:** UNKNOWN
**CAS number:** 25790-35-6
**Category:** other
**FDA GRAS:** no
**Adverse events (FDA AERS):** 0
**FDA recalls:** 0
**Last updated:** 2026-04-02

## Summary

1-(2-furyl)-1,3-butanedione is a synthetic organic compound with a furan ring structure. Its specific function in food applications remains unclear, and it is not approved for use in food by the FDA.

## Regulatory status

| Country | Status |
| --- | --- |
| United States | approved |
| European Union | not_evaluated |
| United Kingdom | not_evaluated |
| Canada | not_evaluated |
| Australia | not_evaluated |
| Japan | not_evaluated |
| South Korea | not_evaluated |
| Brazil | not_evaluated |
| China | not_evaluated |
| India | not_evaluated |

## Detailed analysis

## What is 1-(2-furyl)-1,3-butanedione?

1-(2-furyl)-1,3-butanedione, identified by CAS Number 25790-35-6, is a synthetic organic compound belonging to the class of furan derivatives. The compound consists of a furan ring (a five-membered aromatic ring containing oxygen) attached to a 1,3-butanedione structure. This chemical structure places it in the broader category of carbonyl-containing organic compounds that have been studied in various industrial and research applications.

## Common Uses

The specific food applications and functions of 1-(2-furyl)-1,3-butanedione remain largely undocumented in available food safety literature. While the compound exists in chemical databases and has been referenced in scientific research, its intended use or actual application as a food additive is not clearly established. This lack of documented function distinguishes it from most intentionally added food ingredients, which typically have well-defined roles such as flavoring, preservation, or texture modification.

## Safety Assessment

The safety profile of 1-(2-furyl)-1,3-butanedione remains incomplete due to limited toxicological data available in the public domain. The FDA has received zero adverse event reports associated with this compound, which may reflect either its minimal use in food or the absence of reported health incidents. Similarly, no FDA recalls have been linked to this substance. However, the absence of adverse reports does not constitute a comprehensive safety assessment, as toxicological testing data specific to food use does not appear to be publicly available. Without established safety studies examining absorption, metabolism, and potential toxicity in humans, definitive safety conclusions cannot be drawn.

Furan-containing compounds have been studied due to their presence in heat-processed foods, though most naturally occurring furans are considered generally recognized as safe in their documented uses. However, each compound must be individually assessed based on its specific chemical structure and properties.

## Regulatory Status

1-(2-furyl)-1,3-butanedione is not listed on the FDA's Generally Recognized as Safe (GRAS) list, meaning it has not been formally approved for food use in the United States. It does not appear in FDA Code of Federal Regulations (CFR) sections governing food additives. The European Food Safety Authority (EFSA) does not appear to have established an evaluation for this specific compound in its food additive database. This lack of regulatory approval across major food regulatory bodies indicates that the substance is not authorized for intentional addition to foods in most major markets.

## Key Studies

Published research specifically addressing the safety or efficacy of 1-(2-furyl)-1,3-butanedione in food applications is not readily available in standard scientific literature databases. The compound appears more frequently in synthetic chemistry and organic synthesis literature rather than food science or toxicology journals. Without peer-reviewed safety studies examining the compound's effects in food systems, animal models, or human exposure scenarios, assessment remains limited to its chemical classification and structural analysis. Further research would be necessary to establish whether this compound poses food safety concerns or has legitimate food technology applications.

## Sources

- FDA Substances Added to Food (CFSAN)
- OpenFDA Adverse Event Reporting System (AERS)
- OpenFDA Food Recalls
- EFSA OpenFoodTox
- EU Food Additive Portal

## Citation

Additive Facts. "1-(2-furyl)-1,3-butanedione — Safety, regulation, and evidence." https://additivefacts.com/additives/1-2-furyl-1-3-butanedione. Accessed 2026-05-18.